Hostname: page-component-586b7cd67f-l7hp2 Total loading time: 0 Render date: 2024-11-22T08:24:27.231Z Has data issue: false hasContentIssue false
  • English
  • Français

Two Gases of Gilles de la Tourette's Syndrome Treated with Haloperidol

Published online by Cambridge University Press:  29 January 2018

H. V. Perera
H. V. Perera*
Affiliation:
Ward Place, Colombo 7, Sri Lanka
Get access Rights & Permissions [Opens in a new window]

Summary

Two cases of Gilles de la Tourette's syndrome occurring in Sri Lanka are reported. Both patients had the characteristics of the syndrome as described by Fernando (1967): (1) Childhood onset (below 16 years of age); (2) Multiple motor tics; (3) Unprovoked vocal utterances which may progress to coprolalia. Both responded to haloperidol, withdrawal of medication being followed by relapse, and reintroduction by remission.

The literature on the aetiology of the condition has been reviewed. The weight of evidence favours an organic cause, although psychological precipitation cannot be ruled out.

Type
Papers
Information
The British Journal of Psychiatry , Volume 127 , Issue 4 , October 1975 , pp. 324 - 326
Copyright
Copyright © Royal College of Psychiatrists, 1975 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Challas, G. & Brauer, W. (1963) Tourette's disease: relief of symptoms with R1625. Amer. J. Psychiat, 120, 283–4.CrossRefGoogle ScholarPubMed
Chapel, J. L., Brown, N. & Jenkins, R. L. (1964) Tourette's disease: symptomatic relief with Haloperidol. Amer. J. Psychiat., 121, 608–10.CrossRefGoogle ScholarPubMed
Clark, D. F. (1966) Behaviour therapy in Gilles de la Tourette's syndrome. Brit. J. Psychiat., 112, 117–18.CrossRefGoogle Scholar
Corbett, J. A., Mathews, A. M., Connell, P. H. & Shapiro, D. A. (1969) Tics and Gilles de la Tourette's syndrome: A follow-up study and critical review. Brit. J. Psychiat., 115, 1229–41.CrossRefGoogle ScholarPubMed
Dunlap, J. R. (1960) A case of Gilles de la Tourette's disease (maladie des tics): a study of intrafamilial dynamics. Amer. J. Psychiat., 130, 340–4.Google Scholar
Eisenberg, L., Ascher, E. & Kanner, L. (1959) A clinical study of Gilles de la Tourette's disease (maladie des tics) in children. Amer. J. Psychiat., 115, 715.CrossRefGoogle ScholarPubMed
Fernando, S. J. M. (1967) Gilles de la Tourette's syndrome. Brit. J. Psychiat., 113, 607–17.CrossRefGoogle ScholarPubMed
Friel, P. B. (1973) Familial incidence of Gilles de la Tourette's disease, with observations on aetiology and treatment. Brit. J. Psychiat., 122, 655–8.CrossRefGoogle ScholarPubMed
Morphew, J. A. & Sim, M. (1969) Gilles de la Tourette's syndrome: a clinical and psychopathological study. Brit. J. med. Psychol., 42, 293.CrossRefGoogle ScholarPubMed
Polites, D. J., Kruger, D. & Stevenson, I. (1965) Sequential treatments in a case of Gilles de la Tourette's syndrome. Brit. J. med. Psychol., 38, 43–52.CrossRefGoogle Scholar
Prabhakaran, N. (1970) A case of Gilles de la Tourette's syndrome with some observations on aetiology and treatment. Brit. J. Psychiat., 116, 539–41.CrossRefGoogle ScholarPubMed
Sand, P. L. & Carlson, C. (1973) Failure to establish control over tics in Gilles de la Tourette's syndrome with behaviour therapy techniques. Brit. J. Psychiat., 122, 665–70.CrossRefGoogle ScholarPubMed
Shapiro, A. K. & Shapiro, E. (1968) Treatment of Gilles de la Tourette's syndrome with haloperidol. Brit. J. Psychiat., 114, 345–50.CrossRefGoogle ScholarPubMed
Shapiro, A. K. & Shapiro, E., Wayne, H. & Clarkin, J. (1973) Organic factors in Gilles de la Tourette's syndrome. Brit. J. Psychiat., 122, 659–64.CrossRefGoogle ScholarPubMed
Snyder, S. H., Taylor, K. M., Coyle, J. T. & Meyer-hoff, J. L. (1970) The role of brain dopamine in behavioural regulation and the action of psychotropic drugs. Amer. J. Psychiat., 127, 2.CrossRefGoogle ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.