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Tardive Dyskinesia and Dementia

Published online by Cambridge University Press:  29 January 2018

O. O. Famuyiwa ,
D. Eccleston ,
A. A. Donaldson  and
R. F. Garside
O. O. Famuyiwa
Affiliation:
Bangour Village Hospital, Broxburn, West Lothian
D. Eccleston
Affiliation:
Royal Victoria Infirmary, Newcastle upon Tyne
A. A. Donaldson
Affiliation:
Department of Neuroradiology, Western General Hospital, Edinburgh
R. F. Garside
Affiliation:
Royal Victoria Infirmary, Newcastle upon Tyne
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Summary

Seventeen schizophrenic patients with tardive dyskinesia (TD) and 33 schizophrenics without tardive dyskinesia were examined by psychological tests of intellectual function and EMI scans were performed. The group as a whole were found to be demented and 31 out of 45 had abnormalities on the scan. On a learning test the tardive dyskinesia group did significantly worse and using a measured parameter of the scan (the Ventricular Index) the tardive dyskinesia group had more abnormality. It is suggested that the higher incidence of pathology in the tardive dyskinesia group may be related to chronic neuroleptic toxicity.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 135 , Issue 6 , December 1979 , pp. 500 - 504
Copyright
Copyright © Royal College of Psychiatrists, 1979 

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References

Brandon, S., McClelland, H. A. & Protheroe, C. (1971) A study of facial dyskinesia in a mental hospital population. British Journal of Psychiatry, 118, 171–84.Google Scholar
Christensen, E., M⊘ller, J. & Faurbye, (1970) Neuropathological investigation of 28 brains from patients with dyskinesia. Acta Psychiatrica Scandinavica, 46, 14–23.Google Scholar
Crow, T. J. & Mitchell, W. S. (1975) Subjective age in chronic schizophrenia: evidence for a subgroup of patients with defective learning capacity. British Journal of Psychiatry, 126, 360–3.Google Scholar
Edwards, H. (1970) The significance of brain damage in persistent oral dyskinesia. British Journal of Psychiatry, 116, 271–5.Google Scholar
English, A., Savage, R. D., Britton, P. G., Ward, M. K. & Kerr, D. N. S. (1978) Intellectual impairment in chronic renal failure. British Medical Journal, i, 888–90.Google Scholar
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.Google Scholar
Hinton, J. & Withers, E. (1971) The usefulness of the clinical tests of the sensorium. British Journal of Psychiatry, 119, 9–18.Google Scholar
Inglis, J. (1959) A paired associate learning test for use with psychiatric patients. Journal of Mental Science, 105, 440–3.Google Scholar
Jellinck, E. H. (1976) Cerebral atrophy and congitive impairment in chronic schizophrenia. Lancet, ii, 1202–3.Google Scholar
Johnstone, E. C., Crow, T. J., Frith, C. D., Stevens, M., Kreel, L. & Husband, J. A. (1978) The dementia of dementia praecox. Acta Psychiatrica Scandinavica, 57, 305–24.Google Scholar
Marsden, C. D. (1976) Cerebral atrophy and cognitive impairment in chronic schziophrenia. Lancet, ii, 1079.Google Scholar
Meese, W., Lanksch, W. & Wende, S. (1976) Cerebral atrophy and computerised tomography. In Cranial Computerised Tomography (eds. Lanksch, and Kazner, ). New York: Springer Verlag.Google Scholar
Shapiro, M. B., Post, F., Lofring, B. & Inglish, J. (1956) Memory function in psychiatric patients over sixty, some methological and diagnostic implications. Journal of Mental Science, 102, 233–46.Google Scholar
Trimble, H. & Kingsley, D. (1978) Cerebral ventricular size in chronic schizophrenia. Lancet, i, 278–9.Google Scholar
Walton, D., White, J. G. & Black, D. A. (1959) A modified word learning test: a cross-validation study. British Journal of Medical Psychology, 32, 213–20.Google Scholar
Withers, E. & Hinton, J. (1971) Three forms of the clinical tests of the sensorium and their reliability. British Journal of Psychiatry, 119, 1–8.Google Scholar
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