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A Study of the Immunologic and Allergic Responsiveness of Chronic Schizophrenics

Published online by Cambridge University Press:  29 January 2018

Allen E. Hussar
Affiliation:
Franklin Delano Roosevelt Veterans Administration Hospital, Montrose, New York, U.S.A.
John L. Cradle
Affiliation:
Biochemical Research Laboratory, Franklin Delano Roosevelt Veterans Administration Hospital, Montrose, New York, U.S.A.
Sam M. Beiser
Affiliation:
College of Physicians and Surgeons, Columbia University, New York City, New York, U.S.A.

Extract

Schizophrenic patients are referred to frequently as immunologically incompetent or poor antibody responders. However, if the literature comparing the response of immunized chronic schizophrenics with non-schizophrenic controls is examined, contradictory results may be found (1). Development of allergic responsiveness in schizophrenics as compared to control subjects was also studied with controversial results (4, 2). No studies have been reported in which the antibody response of schizophrenic patients was measured quantitatively simultaneously with the development of an allergic skin reaction following sensitization.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists, 1971 

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References

1. Fessel, W. J. (1962). ‘Blood proteins in functional psychoses. A review of the literature and unifying hypothesis.’ Archives of General Psychiatry, 6, 132–48.CrossRefGoogle ScholarPubMed
2. Freedman, D. X., Redlich, F. C., and Igersheimer, W. W. (1956). ‘Psychosis and allergy: Experimental approach.’ American Journal of Psychiatry, 112, 873–77.CrossRefGoogle ScholarPubMed
3. Kabot, E. A., and Mayer, M. M. (1964). Experimental Immunochemistry. Springfield.Google Scholar
4. Molholm, H. B. (1942). ‘Hyposensitivity to foreign protein in schizophrenic patients.’ Psychiatric Quarterly, 16, 565–71.Google Scholar
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