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Studies of Depressive Symptoms in Schizophrenia

Published online by Cambridge University Press:  29 January 2018

D. A. W. Johnson
D. A. W. Johnson*
Affiliation:
University Hospital of South Manchester, West Didsbury, Manchester M20 8LR
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Summary

Depression assessed by clinical examination and Hamilton rating scale was found in half of 37 untreated new acute schizophrenics, and in about a third of chronic schizophrenics who relapsed whether treated with depot injections (89) or not (79). A significant part of depressive illness in schizophrenics is thus not drug-related. However, depression was commoner in those on higher doses of depot neuroleptic (P <.05) or who showed extrapyramidal side effects (P <.001), suggesting that drugs can play a part. Patients maintained in remission on moderate doses of depot drug had the lowest prevalence of depression.

Type
Papers
Information
The British Journal of Psychiatry , Volume 139 , Issue 2 , August 1981 , pp. 89 - 101
Copyright
Copyright © Royal College of Psychiatrists, 1981 

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