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Somatosensory Evoked Potentials in Schizophrenia a Lateralisation Study

Published online by Cambridge University Press:  02 January 2018

Paul Furlong ,
Paul Barczak ,
Gwilym Hayes  and
Graham Harding
Paul Furlong
Affiliation:
Department of Vision Sciences, Aston University, Birmingham B4 7ET
Paul Barczak*
Affiliation:
Peter Hodgkinson Centre, Lincoln County Hospital, Greetwell Rd, Lincoln LN2 5QY
Gwilym Hayes
Affiliation:
All Saints Hospital, Birmingham
Graham Harding
Affiliation:
Department of Vision Sciences, Aston University
*
∗Correspondence
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Abstract

The SSEPs obtained from 19 schizophrenics defined by RDC, DSM–III and PSE criteria Were compared with those from a control group of healthy volunteers. Previous findings of an abnormal lack of lateralising response in schizophrenic patients were not replicated. No significant difference in either amplitude or morphology between the traces obtained from the two groups were recorded. Ipsilateral and contralateral latencies for stimulation of the left and right index finger showed no significant difference in peak latency for any component between patient and control group. When mean peak-to-peak amplitudes were plotted the contralateral component was always greater in amplitude than the ipsilateral one. An objective measure of the degree of lateralisation, the percentage lateralisation quotient, showed no lateralisation differences between the patient and control groups. A case of myogenic contamination of ipsilateral components was observed calling into doubt findings where no temporal region monitoring has been performed.

Type
Papers
Information
The British Journal of Psychiatry , Volume 157 , Issue 6 , December 1990 , pp. 881 - 887
Copyright
Copyright © The Royal College of Psychiatrists 

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References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd edn) (DSM–III). Washington, DC: APA.Google Scholar
Bickpord, R. G., Jacobson, J. L. & Cody, D. T. R. (1964) Nature of average evoked potentials to sound and other stimuli in man. Annals of New York Academy of Science, 112, 204–223.CrossRefGoogle Scholar
Calmes, R. L. & Cracco, R. Q. (1971) Comparison of somatosensory and somatomotor evoked responses to median nerve and digital nerve stimulation. Electroencephalography and Clinical Neurophysiology, 31, 547–562.CrossRefGoogle ScholarPubMed
Connolly, J. F. (1982) The corpus callosum and brain function in schizophrenia. British Journal of Psychiatry, 140, 429–430.CrossRefGoogle Scholar
Cooper, J. E., Andrews, H. & Barber, C. (1985) Stable abnormalities in the lateralisation of early cortical somatosensory evoked potentials in schizophrenic patients. British Journal of Psychiatry, 146, 585–593.CrossRefGoogle ScholarPubMed
Desmedt, J. E. & Brunko, E. (1980) Functional organisation of the far-field and cortical components of somatosensory evoked potentials in normal adults. In Clinical Uses of Cerebral, Brainstem and Spinal Somatosensory Evoked Potentials, Progress in Clinical Neurophysiology, Vol. 7 (ed. J. E. Desmedt), pp. 264–281. Basel: Karger.Google Scholar
Desmedt, J. E. & Brunko, E. & Cheron, G. (1980) Somatosensory evoked potentials to finger stimulation in healthy octogenarians and in young adults: wave forms, scalp topography and transit times of parietal and frontal components. Electroencephalography and Clinical Neurophysiology, 50, 404–425.CrossRefGoogle ScholarPubMed
Duff, T. A. (1980) Topography of scalp recorded potentials evoked by stimulation of the digits. Electroencephalography and Clinical Neurophysiology, 49, 452–460.CrossRefGoogle ScholarPubMed
Duffy, F. H., Bartels, P. H. & Burchfiel, J. L. (1981) Significance probability mapping: an aid in the topographic analysis of brain electrical activity. Electroencephalography and Clinical Neurophysiology, 51, 455–462.CrossRefGoogle ScholarPubMed
Endicott, J. & Spitzer, R. L. (1978) A diagnostic interview – the schedule for affective disorders and schizophrenia. Archives of General Psychiatry, 35, 837–844.CrossRefGoogle ScholarPubMed
Fenwick, P., Brenna, D. & Philpot, M. (1983) Function of the corpus callosum in schizophrenia. British Journal of Psychiatry, 143, 524.CrossRefGoogle ScholarPubMed
Foit, A., Larsen, B., Hattori, S., et al (1980) Cortical activation during somatosensory stimulation and voluntary movement in man: a regional cerebral blood flow study. Electroencephalography and Clinical Neurophysiology, 50, 426–436.CrossRefGoogle Scholar
Goff, G. D., Matsumiya, Y., Allison, T., et al (1977) The scalp topography of human somatosensory and auditory evoked potentials. Electroencephalography and Clinical Neurophysiology, 42, 57–76.CrossRefGoogle ScholarPubMed
Gulmann, N. C., Wildschiodtz, G. & Ørbaek, K. (1982) Alteration of interhemispheric conduction through the corpus callosum in chronic schizophrenia. Biological Psychiatry, 17, 585–593.Google ScholarPubMed
Halliday, A. M. & Wakefield, G. S. (1963) Cerebral evoked potentials in patients with dissociated sensory loss. Journal of Neurology, Neurosurgery and Psychiatry, 26, 211.CrossRefGoogle ScholarPubMed
Hardin, W. B. & Castellucci, V. F. (1970) Analysis of somatosensory, auditory and visual averaged transcortical and scalp responses in the monkey. Electroencephalography and Clinical Neurophysiology, 28, 488–498.CrossRefGoogle ScholarPubMed
Hyvärinen, J. (1982) The Parietal Cortex of Monkey and Man. New York: Springer Verlag.CrossRefGoogle Scholar
Jones, E. G. & Powell, T. P. S. (1969) Connections of the somatic sensory cortex of the rhesus monkey. II. Contralateral cortical connections. Brain, 92, 717–730.CrossRefGoogle Scholar
Jones, G. H. & Miller, J. J. (1981) Functional tests of the corpus callosum in schizophrenia. British Journal of Psychiatry, 139, 553–557.CrossRefGoogle ScholarPubMed
Kakigi, R. & Shieasaki, H. (1984) Scalp topography of mechanically and electrically evoked somatosensory potentials in man. Electroencephalography and Clinical Neurophysiology, 59, 44–56.CrossRefGoogle ScholarPubMed
Okada, Y. C., Tananbaum, R., Williamson, S. J., et al (1984) Somatotopic organization of the human somatosensory cortex revealed by neuromagnetic measurements. Experimental Brain Research, 56, 197–205.CrossRefGoogle ScholarPubMed
Pratt, H., Poltoske, D. & Starr, A. (1980) Mechanically and electrically evoked somatosensory potentials in humans: effects of stimulus presentation rate. Electroencephalography and Clinical Neurophysiology, 49, 240–249.CrossRefGoogle ScholarPubMed
Pratt, H., & Storr, A. (1981) Mechanically and electrically evoked somatosensory potentials in humans: scalp and neck distributions of short latency components. Electroencephalography and Clinical Neurophysiology, 51, 138–147.CrossRefGoogle ScholarPubMed
Rosenthal, R. & Bigelow, L. B. (1972) Quantitative brain measurement in chronic schizophrenia. British Journal of Psychiatry, 121, 259–264.CrossRefGoogle ScholarPubMed
Salamy, A. (1978) Commisural transmission: maturational changes in humans. Science, 200, 1409–1411.CrossRefGoogle Scholar
Shagass, C., Josiassen, R. C., Roeiner, R. A., et al (1983) Failure to replicate evoked potential observations suggesting corpus callosum dysfunction in schizophrenia. British Journal of Psychiatry, 142, 471–476.CrossRefGoogle ScholarPubMed
Spitzer, R. L., Endicott, J. & Robins, E. (1975) Research Diagnostic Criteria (RDC). Psychopharmacology Bulletin, 11, 22–24.Google Scholar
Suzuki, I. & Mayanagi, Y. (1984) Intracranial recording of short latency somatosensory evoked potentials in man: identification of origin of each component. Electroencephalography and Clinical Neurophysiology, 59, 286–296.CrossRefGoogle ScholarPubMed
Tress, K. H., Caudrey, D. J. & Mehta, B. (1983) Tactile-evoked potentials in schizophrenia. Interhemispheric transfer and drug effects. British Journal of Psychiatry, 143, 156–164.CrossRefGoogle ScholarPubMed
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Syndromes. London: Cambridge University Press.Google Scholar
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