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Sex-Chromatin and Sex-Chromosome Abnormalities in Male Hypogonadal Mental Patients

Published online by Cambridge University Press:  29 January 2018

Johannes Nielsen
Affiliation:
Institute of Psychiatry, Aarhus State Hospital, Risskov, Denmark
Margit Fischer
Affiliation:
Institute of Psychiatry, Aarhus State Hospital, Risskov, Denmark

Extract

The present study is part of a sex-chromatin survey in a mental hospital. It has been made as a preliminary step in finding the prevalence and incidence of sex-chromosome abnormalities among patients with mental illness; and it also has the purpose of studying the psychopathological and genetic aspects of sex-chromosome abnormalities. The study comprises all clinically hypogonadal patients referred by the psychiatrists at this hospital to the cytogenic laboratory during a period of approximately 1 month. In a survey of this kind we can expect to find patients with certain abnormalities of the sex chromosomes.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1965 

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References

Aresin, L. (1960). “Psychische Veränderungen beim Klinefelter-Syndrom.” Psychiat. Neurol. med. Psychol. (Lpz.), 12, 315318.Google Scholar
Barr, M. L., Shover, E. L., Garr, D. H., and Plunkett, E. R. (1960). “The chromatin-positive Klinefelter Syndrome among patients in mental deficiency hospitals.” J. ment. Dep. Res., 4, 89107.Google Scholar
Dengler, K. (1960). “Beitrag zur Psychoendokrinologie des Klinefelter-Syndroms.” Arch. Psychiat. Nervenkr., 200, 626638.Google Scholar
Forssman, H., and Hambert, G. (1963). “Incidence of Klinefelter's syndrome among mental patients.” Lancet, i, 1327.Google Scholar
Heller, C. G., and Nelson, W. O. (1945). “Hyalinization of the seminiferous tubules associated with normal or failing Leydig-cell function. Discussion of relationship to eunuchoidism.” J. din. Endocrin., 5, 1.CrossRefGoogle Scholar
Henriksen, F. (1964). Personal communication.Google Scholar
Klinefelter, H. F., Reifenstein, E. C., and Albright, F. (1942). “Syndrome characterized by gynecomastia, aspermatogenesis without A-Leydigism and increased excretion of follicle-stimulating hormone.” J. clin. Endocrin., 2, 615627.Google Scholar
Maclean, N., Mitchell, J. M., Harnden, D. G., Williams, J., Jacobs, P. A., Buckton, K. A., Baikie, A. G., Court Brown, W. M., McBride, J. A., Strong, J. A., Close, H. G., and Jones, D. C. (1962). “A survey of sex-chromosome abnormalities among 4,514 mental defectives.” Lancet, i, 293296.Google Scholar
Maclean, N., Harnden, D. G., Court Brown, W. M., Bond, J., and Mantle, D. J. (1964). “Sex-chromosome abnormalities in newborn babies.” Lancet, i, 286290.CrossRefGoogle Scholar
Moorhead, P. S., Nowell, P. C., Mellnab, W. J., Battips, D. M., and Hungerford, D. A. (1960.) “Chromosome preparations of leucocytes cultured from human peripheral blood.” Exp. Cell Res., 20, 613616.CrossRefGoogle Scholar
Nielsen, J. (1964). “Prevalence of Klinefelter's Syndrome in patients with mental disorders.” Lancet, 1, 1109.Google Scholar
Nielsen, J. and Olsen, T. (1965). “Psykiske lidelser hos patienter med Klinefelters syndrom.” Ugeskr. Lag. (in the press).Google Scholar
Nielsen, J. and Olsen, T. (1964). “Klinefelter's Syndrome and behaviour.” Lancet, ii, 587588.CrossRefGoogle Scholar
Nielsen, J. and Olsen, T. (1965). “Klinefelter's syndrome in a neurological ward.” Acta neurol. Scand. (in the press).CrossRefGoogle Scholar
Pasqualini, R. Q., Vidal, G., and Bur, G. E. (1957). “Psychopathology of Klinefelter's syndrome.” Lancet, ii, 164167.Google Scholar
Plunkett, E. R., and Barr, M. L. (1956). “Testicular dysgenesis affecting the seminiferous tubules principally with chromatin-positive nuclei.” Lancet, ii, 853857.Google Scholar
Roskamp, H. (1959). “Zur Psychopathologie des Klinefelter-Syndroms.” Arch. Psychiat. Nervenkr., 199, 330344.Google Scholar
Thomsen, O. (1962). “Klinefelters syndrom hos 5 patienter med psykiatriske lidelser.” Ugeskr. Læg., 125, 12761285.Google Scholar
Warburg, E. (1962). “Fertilitet ved Klinefelters Syndrom.” Ibid., 124, 12651276.Google Scholar
Züblin, W. (1954). “Zur Psychologic des Klinefelter-Syndroms.” Acta Endocr., 15, 137144.Google Scholar
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