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Serum Creatine Phosphokinase Elevations in Patients with Tardive Dyskinesia

Published online by Cambridge University Press:  02 January 2018

Michael F. Egan ,
Anissa Abi Dargham ,
Darrelll G. Kirch  and
Richard Jed Wyatt
Michael F. Egan*
Affiliation:
Neuropsychiatry Branch, NIMH Neuroscience Research Center at St Elizabeth's, 2700 M. L. King Junior Avenue, Washington, DC 20032, USA
Anissa Abi Dargham
Affiliation:
Clinical Brain Disorders Branch, Washington, USA
Darrelll G. Kirch
Affiliation:
Division of Clinical Research, Rockville, USA
Richard Jed Wyatt
Affiliation:
Neuropsychiatry Branch, Washington, USA
*
∗Correspondence
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Abstract

We describe a case of marked increases in serum creatine phosphokinase (CPK) associated with a dramatic exacerbation of tardive dyskinesia (TD). Chart review of eight additional patients with severe TD revealed three cases with mild CPK elevations. These cases suggest that TD, especially when accompanied by dystonia, may be associated with pathology of striated muscle.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 162 , Issue 4 , April 1993 , pp. 551 - 553
Copyright
Copyright © Royal College of Psychiatrists, 1993 

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