Hostname: page-component-586b7cd67f-tf8b9 Total loading time: 0 Render date: 2024-11-22T07:52:56.502Z Has data issue: false hasContentIssue false
  • English
  • Français

Serum Copper in Schizophrenia in Nigerians

Published online by Cambridge University Press:  29 January 2018

D. A. Olatunbosun ,
M. O. Akindele ,
B. K. Adadevoh  and
T. Asuni
D. A. Olatunbosun
Affiliation:
University of Ibadan, Ibadan, Nigeria
M. O. Akindele
Affiliation:
University of Ibadan, Ibadan, Nigeria
B. K. Adadevoh
Affiliation:
University of Ibadan, Ibadan, Nigeria
T. Asuni
Affiliation:
Neuro-psychiatric Hospital, Aro, Abeokuta, Nigeria
Get access Rights & Permissions [Opens in a new window]

Summary

Serum copper concentrations were determined by atomic absorption spectrophotometry in 102 schizophrenic patients and 95 healthy control subjects. The serum copper concentrations were significantly higher in the schizophrenic patients than in the normal control subjects. The average serum copper in schizophrenic females was higher than in schizophrenic males, but the difference was not statistically significant

Type
Research Article
Information
The British Journal of Psychiatry , Volume 127 , Issue 2 , August 1975 , pp. 119 - 121
Copyright
Copyright © Royal College of Psychiatrists, 1975 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Adelsttne, S. J. & Vallee, B. L. (1961) Copper metabolism in man. New England Journal of Medicine, 265, 892–7 and 941–6.Google Scholar
Akerfeldt, S. (1957) Oxidation of N.N-di methyl-p-phenylencdiamine by serum from patients with mental illness. Science, 125, 117–19.Google Scholar
Aprison, M. H. & Drew, A. L. (1958) N.N-Dimethyl-p-phenylene diamine oxidation by serum from schizophrenic children. Science, 127, 758.Google Scholar
Asuni, T. (1967) Aro Hospital in perspective. American Journal of Psychiatry, 124, 763–70.CrossRefGoogle Scholar
Bakwin, R. M., Mosbach, E. H. & Bakwin, H. (1958) Caeruloplasmin activity in the serum of children with schizophrenia. Pediatrics, 22, 905–9.Google Scholar
Bakwin, R. M., Mosbach, E. H. & Bakwin, H. (1961) Concentration of copper in serum of children with schizophrenia. Pediatrics, 27, 642–4.Google Scholar
Chugh, T. D., Dhingra, R. K., Gulati, R. C. & Bathla, J. C. (1973) Copper metabolism in schizophrenia Indian Journal of Medical Research, 61, 1147–52.Google Scholar
Olatunbosun, D. A., Adeniyi, F. A. & Adadevoh, B. K. (1973) The effect of oral contraceptives on serum copper levels in Nigerian women. Journal of Obstetrics and Gynaecology of the British Commonwealth, 80, 937–9.CrossRefGoogle ScholarPubMed
Pfeiffer, C. C. (1971) A longitudinal study of tracemetal therapy in the copper-loaded schizophrenic patient. Psychopharmacological Bulletin, 7, 33–4.Google Scholar
Pfeiffer, C. C. & Iliev, V. (1972) A study of zinc deficiency and copper excess in the schizophrenias. International Review of Neurobiolog. Supplement 1, 141–65.Google Scholar
Sinha, S. N. & Gabrielli, E. R. (1970) Serum copper and zinc levels in various pathological conditions. American Journal of Clinical Pathology, 54, 570–7.Google Scholar
Scheinberg, J. H., Morrell, A. G., Harris, R. S. & Beroer, A. (1957) Concentration of ceruloplasmin in plasma of schizophrenic patients. Science, 126, 925–6.Google Scholar
United States of America, Department of Health, Education Hand Welfare (1967) Republic of Nigeria Nutrition Survey, February–April 1965, p. 96.Google Scholar
White, A., Handler, P. & Smith, E. L. (1968) Principles of Biochemistry. New York: McGraw-Hill.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.