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The Scottish First Episode Schizophrenia Study

VIII. Five-Year Follow-Up: Clinical and Psychosocial Findings

Published online by Cambridge University Press:  02 January 2018

Robin G. McCreadie ,
David H. Wiles ,
Martin G. Livingston ,
James A. G. Watt ,
J. G. Greene ,
Peter W. Kershaw ,
Norman A. Todd ,
Angus M. Scott ,
George T. Crocket  and
Zahid Mahmood
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Robin G. McCreadie*
Affiliation:
Crichton Royal Hospital, Dumfries DG1 4TG
David H. Wiles
Affiliation:
Crichton Royal Hospital, Dumfries DG1 4TG
Martin G. Livingston
Affiliation:
Gartnavel Royal Hospital, Glasgow G12 0YN
James A. G. Watt
Affiliation:
Gartnavel Royal Hospital, Glasgow G12 0YN
J. G. Greene
Affiliation:
Gartnavel Royal Hospital, Glasgow G12 0YN
Peter W. Kershaw
Affiliation:
Gartnavel Royal Hospital, Glasgow G12 0YN
Norman A. Todd
Affiliation:
Leverndale Hospital, Glasgow G53 7TU
Angus M. Scott
Affiliation:
Leverndale Hospital, Glasgow G53 7TU
George T. Crocket
Affiliation:
Parkhead Hospital, Glasgow G31 5BA
Zahid Mahmood
Affiliation:
Parkhead Hospital, Glasgow G31 5BA
John Loudon
Affiliation:
Royal Edinburgh Hospital, Edinburgh EH10 5HF
James A. T. Dyer
Affiliation:
Royal Edinburgh Hospital, Edinburgh EH10 5HF
Alistair E. Philip
Affiliation:
Royal Edinburgh Hospital, Edinburgh EH10 5HF
David Batchelor
Affiliation:
Janssen Pharmaceutical Limited, Grove, Wantage, Oxon
*
∗Correspondence
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Abstract

Forty-four schizophrenic patients were followed up for five years after their first admission to hospital for a first episode of illness. Thirteen (30%) of 43 patients had not relapsed; 28 of the 30 patients who did relapse did so within the first 42 months. The relapses occurred despite antipsychotic drug therapy. Also, 24% of patients had at least one course of ECT. Only 19% of the patients at five years were in open employment; unemployment was strongly associated with relapse. Eighteen per cent had neither relapses nor schizophrenic symptoms at follow-up. Poor outcome at five years was associated with greater psychological distress among relatives at first admission. At five years 43% of relatives continued to show case level psychological stress.

Type
Papers
Information
The British Journal of Psychiatry , Volume 161 , Issue 4 , October 1992 , pp. 496 - 500
Copyright
Copyright © 1992 The Royal College of Psychiatrists 

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References

Feighner, J. P., Robins, E., Guze, S., et al (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–62.Google Scholar
Finlay-Jones, R. A. & Burvill, P. W. (1977) The prevalence of psychiatric morbidity in the community. Psychological Medicine, 7, 475–489.Google Scholar
Goldberg, D. & Hillier, V. F. (1979) A scaled version of the General Health Questionnaire. Psychological Medicine, 9, 139–146.Google Scholar
Grad, J. & Sainsbury, P. (1968) The effects that patients have on their families in a community care and control psychiatric service: a two year follow-up. British Journal of Psychiatry, 114, 265–278.Google Scholar
Helgason, L. (1990) Twenty years' follow-up of first psychiatric presentation for schizophrenia: what could have been prevented? Acta Psychiatrica Scandinavica, 81, 231–235.Google Scholar
Hoenig, J. & Hamilton, M. W. (1966) The schizophrenic patient in the community and his effect on the household. International Journal of Social Psychiatry, 12, 165–176.Google Scholar
Krawiecka, M., Goldberg, D. & Vaughn, M. (1977) A standardised psychiatric assessment scale for rating psychotic patients. Acta Psychiatrica Scandinavica, 55, 299–308.Google Scholar
Kuipers, L., MacCarthy, B., Hurry, J., et al (1989) Counselling the relatives of the long-term adult mentally ill. A low-cost supportive method. British Journal of Psychiatry, 154, 775–782.Google Scholar
Leff, J. P., Kuipers, L., Berkowitz, R., et al (1982) A controlled trial of social intervention in the families of schizophrenic patients. British Journal of Psychiatry, 141, 121–134.Google Scholar
Munk-Jorgensen, P. & Mortensen, P. B. (1989) Schizophrenia: a 13 year follow-up. Acta Psychiatrica Scandinavica, 79, 391–399.Google Scholar
Murray, R. M. & O'Callaghan, E. (1991) Neurodevelopmental schizophrenia. Schizophrenia Monitor, 1, 1–3.Google Scholar
Prudo, R. & Munroe-Blum, H. (1987) Five-year outcome and prognosis in schizophrenia: a report from the London field research centre and the International Pilot Study of Schizophrenia. British Journal of Psychiatry, 150, 345–354.Google Scholar
Rabiner, C. J., Wegner, J. T. & Kane, J. M. (1986) Outcome study of first episode psychosis. I Relapse rates after one year. American Journal of Psychiatry, 143, 1155–1158.Google Scholar
Scottish Schizophrenia Research Group (1987a) The Scottish First Episode Schizophrenia Study. I Patient identification and categorisation. British Journal of Psychiatry, 150, 331–333.Google Scholar
Scottish Schizophrenia Research Group (1987b) The Scottish First Episode Schizophrenia Study. II Treatment: pimozide versus flupenthixol. British Journal of Psychiatry, 150, 334–338.Google Scholar
Scottish Schizophrenia Research Group (1987c) The Scottish First Episode Schizophrenia Study. III Cognitive performance. British Journal of Psychiatry, 150, 338–340.Google Scholar
Scottish Schizophrenia Research Group (1987d) The Scottish First Episode Schizophrenia Study. IV—Psychiatric and social impact on relatives. British Journal of Psychiatry, 150, 340–344.Google Scholar
Scottish Schizophrenia Research Group (1988) The Scottish First Episode Schizophrenia Study. V—One year follow-up. British Journal of Psychiatry, 152, 470–476.Google Scholar
Scottish Schizophrenia Research Group (1989) The Scottish First Episode Schizophrenia Study. VII Two year follow-up. Acta Psychiatrica Scandinavica, 80, 597–602.Google Scholar
Scottish Schizophrenia Research Group, MacDonald, H. L. & Best, J. J. K. (1989) The Scottish First Episode Schizophrenia Study. VI Computerised tomography brain scans in patients and controls. British Journal of Psychiatry, 154, 492–498.Google Scholar
Shepherd, M., Watt, D., Falloon, I., et al (1989) The natural history of schizophrenia: a five year follow-up study of outcome and prediction in a representative sample of schizophrenics. Psychological Medicine (suppl. 15) 18–19.Google Scholar
Simpson, G. M. & Angus, J. W. S. (1970) A rating scale for extrapyramidal side effects. Acta Psychiatrica Scandinavica (suppl. 212), 11–19.Google Scholar
Spitzer, R., Endicott, J. & Robins, E. (1978) Research Diagnostic Criteria Instrument, No. 58. New York: New York State Psychiatric Institute.Google Scholar
United States Department of Health, Education a Welfare (1976) Abnormal Involuntary Movements Scale (AIMS). In ECDEU Assessment Manual (ed. W. Guy), pp. 535–537. Rockville, Maryland: US Department of Health, Education and Welfare.Google Scholar
Weissman, M. M. & Bothwell, S. (1976) Assessment of social adjustment by patients' self-report. Archives of General Psychiatry, 33, 1111–1115.Google Scholar
Weissman, M. M., Prusoff, B. A., Thompson, W. D., et al (1978) Social adjustment by self-report in a community sample and in schizophrenic outpatients. Journal of Nervous and Mental Disease, 166, 317–326.Google Scholar
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Symptoms. London: Cambridge University Press.Google Scholar
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