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Published online by Cambridge University Press: 29 January 2018
Erythropoietic Protoporphyria (E.P.P.) may be classified along with the other erythropoietic syndromes of porphyria. It is inherited as an autosomal dominant (Taddeini and Watson, 1968). The condition was first clearly delineated by Magnus, Jarrett, Prankerd and Rimington (1961). They recorded a case with the presenting symptom of solar urticaria in whom faecal excretion of coproporphyrin and protoporphyrin was greatly increased while urinary porphyrins were normal. The red cells contained grossly abnormal amounts of protoporphyrin and coproporphyrin, the plasma increased levels of protoporphyrin. The absence of uroporphyrin distinguished this condition from congenital porphyria (Gunther's Disease).
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