Hostname: page-component-cd9895bd7-hc48f Total loading time: 0 Render date: 2024-12-22T16:34:15.142Z Has data issue: false hasContentIssue false
  • English
  • Français

The Role of Zinc in Senile Dementia

Published online by Cambridge University Press:  29 January 2018

Chris Kenn  and
Elizabeth Gibb
Chris Kenn*
Affiliation:
St James's Hospital, Beckett Street, Leeds 9
Elizabeth Gibb
Affiliation:
Leeds Psychiatric Rotation Training Scheme
*
∗Correspondence
Get access Rights & Permissions [Opens in a new window]

Abstract

Zinc deficiency has been reported in association with dementia and linked with its pathogenesis. A group of 45 elderly patients admitted to a mental hospital were given diagnoses in accordance with ICD-9, and their fasting plasma zinc levels were recorded. No difference was found in zinc levels between patients with diagnoses of senile dementia and those with other diagnoses.

Type
Papers
Information
The British Journal of Psychiatry , Volume 149 , Issue 2 , August 1986 , pp. 221 - 223
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abdulla, M. (1983) How adequate is plasma zinc as an indicator of zinc status? In Zinc Deficiency in Human Subjects: Progress in Clinical and Biological Research, 129. New York: Liss.Google Scholar
American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders (3rd ed.) (DSM-III). Washington DC: APA.Google Scholar
British Medical Journal (1981) Another look at zinc. British Medical Journal, 282, 1098–1099.Google Scholar
Bunker, V. W., Hinks, L. J., Lawson, M. S. & Clayton, B. E. (1984) Assessment of a zinc and copper status of healthy elderly people using metabolic balance studies and measurement of leucocyte concentrations. American Journal of Clinical Nutrition, 40, 1096–1102.Google Scholar
Burnet, F. M. (1981) A possible role of zinc in the pathology of dementia. The Lancet, i, 186–188.Google Scholar
Bryct-Smith, D. & Simpson, R. I. D. (1984) Case of anorexia nervosa responding to zinc sulphate. The Lancet, ii, 350.Google Scholar
Casper, R. C., Kirscher, B., Sandstead, H. H., Hacob, R. A. & Davb, J. M. (1980) An evaluation of trace metals, vitamins and taste function in anorexia nervosa. American Journal of Clinical Nutrition, 33, 1801–1808.Google Scholar
Hachtnski, V. C., Lassen, N. A., & Marshall, J. (1974) Multi infarct dementia: a cause of mental deterioraion in the elderly. The Lancet, ii, 207–210.Google Scholar
Halsted, J. A. & Smith, J. C. (1970) Plasma zinc in health and disease. The Lancet, i, 322–324.Google Scholar
Henkin, R. I., Patten, B. M., Re, P. K. & Bronzert, D. A. (1975) A syndrome of acute zinc loss. Archives of Neurology, 32, 745–751.CrossRefGoogle ScholarPubMed
Hullin, R. P. (1983) Serum zinc in psychiatric patients In Zinc Deficiency in Human Subjects: Progress in Clinical Biological Research, 129. New York: Liss.Google Scholar
Kay, R. G., Tasman-Jones, C., Pybus, J., Whiting, R. & Black, H. (1976) A syndrome of acute zinc deficiency during total parenteral alimentation in man. Annals of Surgery, 183, 331–340.Google Scholar
Kosman, D. J. & Jenktn, R. I. (1979) Plasma and scrum zinc concentrations. The Lancet, i, 1410.CrossRefGoogle Scholar
Nelder, K. H. & Hambridge, K. M. (1975) Zinc therapy of acrodermatitis enteropathica. New England Journal of Medicine, 292, 879–882.CrossRefGoogle Scholar
Prasad, A. S. (1983) Clinical, biochemical and nutritional spectrum of zinc deficiency in human subjects: an update. Nutritional Reviews, 41, 197–206.CrossRefGoogle ScholarPubMed
Srintvasan, D. P. (1984) Trace elements in psychiatric illness. British Journal of Hospital Medicine, 32, 77–79.Google Scholar
Tiggelen, C. J. M. (1983) Zinc deficiency, a possible co-factor in pathological ageing In Trace Elements: Health and Hair Analysis, 63–74. Netherlands: IMS Brada.Google Scholar
Whitehouse, R. C., Prasad, A. S., Rabbani, P. I. & Cossack, Z. T. (1982) Zinc in plasma, neutrophils, lymphocytes and erythocytes as determined by nameless atomic absorption spectrophotometry. Clinical Chemistry, 28, 475–480.Google Scholar
World Health Organization (1975) Manual of the International Statistical Classification of Diseases, Injuries and Causes of Death (9th revision) (ICD-9). Geneva: WHO.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.