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A Review of Clinical Experience

Published online by Cambridge University Press:  29 January 2018

Andrew Skarbek  and
Michael Jacobsen
Andrew Skarbek
Affiliation:
Psycholinguistic Research Unit, University College London
Michael Jacobsen
Affiliation:
Clinical Evaluation Unit, The Bayer Products Company, Surbiton, Surrey
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Extract

Oxypertine (also known as WIN 18,501–2) is a member of a new series of indolylalkylphenyl-piperazines synthesized by Archer et al (1). It resembles serotonin in respect of its indole nucleus, and the piperazine side-chain indicates a structural relationship with some of the major phenothiazines. Pharmacological studies by Wylie and Archer (17) showed oxypertine to have tranquillizing properties, and following preliminary human tolerance investigations (15) the psychotherapeutic nature of the agent was investigated by various workers in the United States and Europe.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 111 , Issue 481 , December 1965 , pp. 1173 - 1179
Copyright
Copyright © Royal College of Psychiatrists, 1965 

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References

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