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Respiratory Ventilation and Carbon Dioxide Levels in Syndromes of Depression

Published online by Cambridge University Press:  29 January 2018

J. Damas Mora
Affiliation:
Especialista em Psiquitria (Portugal), Lecturer in Psychiatry, University of Sheffield, Attached Worker of the MRC Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TD
L. Grant
Affiliation:
MRC Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP
Patricia Kenyon
Affiliation:
MRC Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP
M. K. Patel
Affiliation:
Visiting Biostatistican from the University of Illinois Medical Center
F. A. Jenner
Affiliation:
University of Sheffield; and Honorary Director of the Medical Research Council Unit for Metabolic Studies in Psychiatry, Sheffield S6 1TP

Summary

The breathing rate and PCO2 in end-tidal air have been studied in controls and in patients with endogenous depression (retarded and non-retarded), with neurotic depression, and with schizophrenia. It has been shown that breathing rate goes up and PCO2 down in non-retarded and neurotic depression. Schizophrenia gives more anomalous results. The fact is emphasized that such changes must lead to alterations in pH and other variables. Studies showing some small chemical differences between these clinical entities and control subjects might therefore be explained by these findings.

Type
Papers
Copyright
Copyright © Royal College of Psychiatrists, 1976 

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