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The Reproducibility of the Mecholyl Test

Published online by Cambridge University Press:  29 January 2018

Charles G. Ingram  and
Walter G. Brovins
Charles G. Ingram
Affiliation:
Department of Physiology, St. Salvators College, University of S. Andrews, Fife, Scotland
Walter G. Brovins
Affiliation:
Ypsilanti State Hospital, Ypsilanti, Michigan, U.S.A
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Extract

The blood pressure response to the injection of the parasympathomimetic drug methacholine (Mecholyl) has been used extensively in psychiatry to delineate various aspects of mental disease. Although originally used in diagnostic classification (Altman et al., 1943), its use, following the investigations of Funkenstein and his co-workers (1948, 1952), has more often been as an aid in prognosis or as a guide to the most useful type of somatic therapy. Investigations into this aspect of the test have resulted in many contradictory reports, and even after so many years there is still no agreement on the test's validity or usefulness.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 112 , Issue 483 , February 1966 , pp. 167 - 171
Copyright
Copyright © Royal College of Psychiatrists, 1966 

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