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The Prediction of Abnormal Evoked Potentials in Schizophrenic Patients by Means of Symptom Pattern

Published online by Cambridge University Press:  29 January 2018

Harry B. Andrews*
Affiliation:
Department of Psychiatry
Allan O. House
Affiliation:
Department of Psychiatry
John E. Cooper
Affiliation:
Department of Psychiatry
Colin Barber
Affiliation:
The Medical School, Queen's Medical Centre, The University, Clifton Boulevard, Nottingham NG7 2UH
*
Correspondence

Abstract

The case notes of 23 schizophrenic patients who participated in a study of somato-sensory cortical evoked responses were examined for descriptions of the clinical features of their mental state at the time of first illness or most recent relapse. A comparison of syndrome scores derived from Present State Examination with those derived from case notes showed that the latter was a reliable method of mental state description for the purposes of this study. A group of syndromes similar to that described in electrodermal research was identified from the case note review and found to be highly correlated with the presence of an abnormal response in the somato-sensory evoked potentials study.

Type
Papers
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

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References

Allison, T., Goff, W. R., Williamson, P. D. & Van Glider, J. C. (1980) The neural origin of early components of the human somatosensory evoked potential. Progress in Clinical Neurophysiology, 7, 5168.Google Scholar
Bleuler, E. (1911) Dementia Praecox or the Groups of Schizophrenia (transi 1950). New York: International Universities Press.Google Scholar
Connolly, J. F., Manchanda, R., Gruzelier, J. H. & Hirsch, S. R. (1985) Pathway and hemispheric differences in the event-related potential (ERP) to monaural stimulation: a comparison of schizophrenic patients with normal controls. Biological Psychiatry, 20, 293303.CrossRefGoogle ScholarPubMed
Cooper, J. E., Andrews, H. B. & Barber, C. (1985) Stable abnormalities in the lateralisation of early cortical evoked somato-sensory responses in schizophrenic patients. British Journal of Psychiatry, 146, 585593.CrossRefGoogle Scholar
Flor-Henry, P. (1983) The Cerebral Basis of Psychopathology. Chichester: John Wiley.Google Scholar
Geschwind, N. (1965) Disconnection syndromes in animals and man. Brain, 88, 237294.CrossRefGoogle ScholarPubMed
Gruzelier, J. H. (1983) A critical assessment and integration of lateral asymmetries in schizophrenia In Hemisyndromes: Psychobiology, Neurology, Psychiatry, London: Academic Press.Google Scholar
Gruzelier, J. H. & Manchanda, R. (1982) The syndrome of schizophrenia: relation between electrodermal responses, lateral asymmetries and clinical ratings. British Journal of Psychiatry, 141, 488495.CrossRefGoogle ScholarPubMed
Hirsch, S. R., Gaind, R., Rowde, P. D., Stevens, B. C. & Wing, J. K. (1973) Out-patient maintenance of chronic schizophrenic patients with long-acting fluphenazine: double-blind placebo trial. British Medical Journal, 276, 633637.CrossRefGoogle Scholar
Jutai, J. W., Gruzelier, J. H., Connolly, J. F., Manchanda, R. & Hirsch, S. R. (1984) Schizophrenia and spectral analysis of the visual evoked potential. British Journal of Psychiatry, 145, 496501.CrossRefGoogle ScholarPubMed
Kety, S. S. (1980) The syndrome of schizophrenia: unresolved questions and opportunities for research. British Journal of Psychiatry, 136, 421436.CrossRefGoogle ScholarPubMed
Langfeldt, G. (1960) Diagnosis and prognosis in schizophrenia. Proceedings of the Royal Society of Medicine, 53, 10471051.CrossRefGoogle ScholarPubMed
Pratt, H., Amelie, R. W. & Starr, A. (1979) Short latency mechanically evoked somato-sensory potentials in humans. Electroencephalography and Clinical Neurophysiology, 47, 496501.CrossRefGoogle Scholar
Walker, E. & McGuire, M. (1982) Intra- and inter-hemispheric information processing in schizophrenia. Psychological Bulletin, 92, 701725.CrossRefGoogle Scholar
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Syndromes. London: Cambridge University Press.Google Scholar
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