Hostname: page-component-586b7cd67f-rdxmf Total loading time: 0 Render date: 2024-11-22T08:08:19.789Z Has data issue: false hasContentIssue false
  • English
  • Français

Pituitary and Adrenal Function in Undernutrition with Mental Illness

(including Anorexia Nervosa)

Published online by Cambridge University Press:  29 January 2018

V. Marks  and
R. G. Bannister
V. Marks
Affiliation:
Area Laboratory, at West Park Hospital, Epsom, Surrey
R. G. Bannister
Affiliation:
University Unit in Clinical Neurology, The National Hospital, Queen Square, London
Get access Rights & Permissions [Opens in a new window]

Extract

Urinary excretion of adrenal metabolites, especially neutral 17-ketosteroids, is often low in patients with anorexia nervosa (Escamilla, 1949; Bliss and Branch, 1960). This has been taken (Emanuel, 1956; Greenblatt et al., 1951) to provide evidence of adreno-cortical insufficiency secondary to defective pituitary function (Sheldon, 1939; Perloff et al., 1954). According to Perloff et al. (1954) “prolonged starvation may result in functional hypopituitarism, whose differentiation from the syndrome of hypopituitary cachexia due to structural impairment of the anterior pituitary gland is at times extremely difficult, even when the accepted tests for endocrine adequacy are performed”.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 109 , Issue 461 , July 1963 , pp. 480 - 484
Copyright
Copyright © Royal College of Psychiatrists, 1963

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Appleby, J. I., Gibson, G., Norymberski, J. K., and Stubbs, R. O. (1955). Biochem. J., 60, 453.CrossRefGoogle Scholar
Buss, E. L., and Branch, C. H. H. (1960). Anorexia Nervosa. Its History, Psychology and Biology. New York: Hoeber.Google Scholar
Buss, E. L. and Migeon, C. (1957). J. Clin. Endocrinol., 17, 766.Google Scholar
Buss, E. L., Sandberg, A. A., Nelson, D. H., and Eik-Nes, K. (1953). J. Clin. Invest., 32, 818.Google Scholar
Cleveland, W. W., Green, O. C., and Migeon, C. J. (1960). J. Pediat., 57, 376.CrossRefGoogle Scholar
Dennis, P. M., and Hall, J. G. (1962). N.Z. Med. J., 61, 153.Google Scholar
Emanuel, R. W. (1956). J. Clin. Endocrin., 16, 801.CrossRefGoogle Scholar
Escamilla, R. F. (1949). Ann. Intern. Med., 30, 249.Google Scholar
Greenblatt, R. B., Barfield, W. E., and Clark, S. L. (1951). J. Med. Ass. Georgia, 40, 299.Google Scholar
King, E. J., and Wootton, I. (1956). Micro-Analysis in Medical Biochemistry (3rd. Ed.). Churchill.Google Scholar
Liddle, G. W., Estep, H. L., Kendall, J. W., Williams, W. C., and Townes, A. W. (1959). J. Clin. Endocrin., 19, 875.CrossRefGoogle Scholar
Marks, V. (1962). Lancet, i, 1409.CrossRefGoogle Scholar
Marks, V. and Summers, M. (1963). Brit. Med. J., in press.Google Scholar
Norymberski, J. K., Stubbs, R. O., and West, H. F. (1953). Lancet, i, 1276.Google Scholar
Paris, J. (1961). Proc. Mayo. Clin., 36, 305.Google Scholar
Perloff, W. H., Lasche, E. M., Nodine, J. H., Schneeberg, N. G., and Viellard, C. B. (1954). J. Amer. Med. Ass., 155, 1307.CrossRefGoogle Scholar
Sheldon, J. H. (1939). Proc. R. Soc. Med., 32, 738.Google Scholar
Vestergaard, P., and Leverett, R. (1958). J. Lab. Clin. Med., 51, 211.Google Scholar
Williams, G. A., Crispell, K. R., and Parsons, W. (1957). J. Clin. Endocrinol., 17, 1347.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.