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Patterns of Peptides and Protein-Associated-Peptide Complexes in Psychiatric Disorders

Published online by Cambridge University Press:  29 January 2018

O. E. Trygstad ,
K. L. Reichelt ,
I. Foss ,
P. D. Edminson ,
G. Saelid ,
J. Bremer ,
K. Hole ,
H. Ørbeck ,
J. H. Johansen  and
J. B. B⊘ler
...Show all authors
O. E. Trygstad
Affiliation:
Institute of Pediatric Research, Rikshospitalet, University Hospital, Oslo 1, Norway
K. L. Reichelt*
Affiliation:
Institute of Pediatric Research, Rikshospitalet, University Hospital, Oslo 1, Norway
I. Foss
Affiliation:
Institute of Pediatric Research, Rikshospitalet, University Hospital, Oslo 1, Norway
P. D. Edminson
Affiliation:
Institute of Pediatric Research, Rikshospitalet, University Hospital, Oslo 1, Norway
G. Saelid
Affiliation:
Institute of Pediatric Research, Rikshospitalet, University Hospital, Oslo 1, Norway
J. Bremer
Affiliation:
Gaustad Hospital, University of Oslo, Oslo, Norway
K. Hole
Affiliation:
Department of Physiology, University of Bergen, Bergen, Norway
H. Ørbeck
Affiliation:
Institute of Pediatric Research, Rikshospitalet, University Hospital, Oslo 1, Norway
J. H. Johansen
Affiliation:
Department of Chemistry, University of Oslo, Blindern, Norway
J. B. B⊘ler
Affiliation:
Department of Chemistry, University of Oslo, Blindern, Norway
K. Titlestad
Affiliation:
Department of Chemistry, University of Oslo, Blindern, Norway
P. K. Opstad
Affiliation:
Norwegian Defence Research Establishment, Kjeller, Norway
*
∗ Address for correspondence.
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Summary

Peptidic neurones may be considered as multisignal integrators and transducers. When formation or release of peptide outstrips genetically determined breakdown capacity, overflow of peptides to the body fluids and urine may be expected. In this paper, pathological urinary chromatographic patterns of peptides are shown for genetic, functional and mixed disorders. Part symptoms of the disorders may be induced with the biologically isolated and purified peptides as well as with chemically synthesized peptides.

Type
Papers
Information
The British Journal of Psychiatry , Volume 136 , Issue 1 , January 1980 , pp. 59 - 72
Copyright
Copyright © The Royal College of Psychiatrists 

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