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Panic Symptoms after Inhalation of Carbondioxide

Published online by Cambridge University Press:  29 January 2018

Marcel A. van den Hout  and
Eric Griez
Marcel A. van den Hout
Affiliation:
Department of Medical Psychology, State University of Limburg, P.O. Box 616, 6200 MD Maastricht, Netherlands
Eric Griez
Affiliation:
Department of Clinical Psychiatry, State University of Limburg
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Summary

The effects of inhaling a mixture of 35 per cent carbon dioxide and 65 per cent oxygen on the occurrence of panic symptoms defined by the DSM III, was investigated. Compared to a placebo (air), carbon dioxide produced more panic symptoms. If carbon dioxide inhalation was preceded by intake of a beta-blocker (60 mg propranolol), less symptoms occurred than if preceded by a placebo. The results are compared with earlier reports on the effects of lactate infusion. It is argued that panic disorders can be conceptualized as a fear of internal (panic) sensations and that inhalation of a mixture of carbon dioxide and oxygen may constitute an effective exposure treatment.

Type
Papers
Information
The British Journal of Psychiatry , Volume 144 , Issue 5 , May 1984 , pp. 503 - 507
Copyright
Copyright © 1984 The Royal College of Psychiatrists 

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References

Ackerman, S. H. & Sachar, E. J. (1974) The lactate theory of anxiety. A review and re-evaluation. Psychosomatic Medicine, 36, 69–90.CrossRefGoogle Scholar
Arbab, A. G., Bonn, J. A. & Hicks, D. C. (1971) Effect of propranolol on lactate induced phenomena in normal subjects. British Journal of Pharmacology, 41, 430.Google ScholarPubMed
Bonn, J. A., Harrison, J. & Rees, W. L. (1971) Lactate induced anxiety: therapeutic applications. British Journal of Psychiatry, 119, 468–71.CrossRefGoogle Scholar
Evans, I. M. (1972) A conditioning model of a common neurotic pattern—fear of fear. Psychotherapy, Theory, Research and Practice, 9, 238–41.Google Scholar
Griez, E. & Van den Hout, M. A. (1982) Effects of carbondioxide-oxygen inhalations on subjective anxiety and some neurovegetative parameters. Journal of Behavior Therapy and Experimental Psychiatry, 13, 27–32.Google Scholar
Griez, E. & Van den Hout, M. A. (1983a) Treatment of phobophobia by exposure to CO2 induced anxiety symptoms. Journal of Nervous and Mental Disease, 171, 506–8.Google Scholar
Griez, E. & Van den Hout, M. A. (1983b). Carbondioxide and anxiety. Cardiovascular effects of a single inhalation. Journal of Behavior Therapy and Experimental Psychiatry, 14, 297–304.CrossRefGoogle Scholar
Grosz, H. J. & Farmer, B. B. (1972) Pitt's and McClure's lactate-anxiety study revisited. British Journal of Psychiatry, 120, 415–18.Google Scholar
Hout Van den, M. A. & Griez, E. (1982a) Cardiovascular and subjective responses to inhalation of carbondioxide. Psychotherapy and Psychosomatics, 37, 75–82.Google Scholar
Hout Van den, M. A. & Griez, E. (1982b) Cognitive factors in carbondioxide therapy. Journal of Psychosomatic Research, 26, 209–14.Google Scholar
Kelly, D., Mitchell-Heggs, N. & Shermann, D. (1971) Anxiety and the effects of sodium lactate assessed clinically and physiologically. British Journal of Psychiatry, 119, 129–41.Google Scholar
Latimer, P. (1977) Carbondioxide as a reciprocal inhibitor in the treatment of neurosis. Journal of Behavior Therapy and Experimental Psychiatry, 8, 83–5.Google Scholar
Ley, R. & Walker, H. (1973) Effects of carbondioxide-oxygen inhalation on heart rate, blood pressure and subjective anxiety. Journal of Behavior Therapy and Experimental Psychiatry, 4, 223–8.CrossRefGoogle Scholar
Linder, W. (1981) Exposure therapy for vocal phobias: a review. Archives of General Psychiatry, 38, 769–75.Google Scholar
Marks, I. M. (1978) Exposure treatments: conceptual issues and clinical applications. In Behavior Modification: Principles and Clinical Applications (ed. W. S. Agras). Boston: Little Brown.Google Scholar
Pitts, F. N. & McClure, J. N. (1967) Lactate metabolism in anxiety neurosis. New England Journal of Medicine, 277, 1329–36.Google Scholar
Slater, S. L. & Levy, A. (1966) The effects of inhaling a 35 per cent CO2–65 per cent O2 mixture upon anxiety in neurotic patients. Behavior Research and Therapy, 4, 309–16.CrossRefGoogle ScholarPubMed
Wheatly, D. (1981) Beta-blocking drugs in anxiety. In Stress and the Heart (ed. D. Wheatly). New York: Raven Press.Google Scholar
Wolpe, J. (1958) Psychotherapy by Reciprocal Inhibition. Stanford, California: Stanford University Press.Google Scholar
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