Hostname: page-component-cd9895bd7-gxg78 Total loading time: 0 Render date: 2024-12-22T16:05:26.030Z Has data issue: false hasContentIssue false

The Outcome of Severe Acute Schizophrenic Illnesses After One Year

Published online by Cambridge University Press:  29 January 2018

Eve C. Johnstone
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ
C. D. Frith
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ
Aviva Gold
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ
Marilyn Stevens
Affiliation:
Department of Psychiatry, Northwick Park Hospital and Clinical Research Centre, Watford Road, Harrow, Middlesex, HA1 3UJ

Summary

Forty-five patients with acute schizophrenic illnesses (defined by PSE criteria) were assessed in clinical, cognitive and social terms before being entered in a four week study of the isomers of flupenthixol and placebo. At the end of one year they were re-assessed in the same terms. The clinical and psychological features of the acute illness and the drug treatment given did not predict outcome. Poor outcome in social terms was significantly related to severe social isolation in the initial assessment and to the presence of nuclear symptoms and negative schizophrenic features at follow-up.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Brockington, I. F. & Kendell, R. E. Criteria for a diagnosis of schizo-affective psychosis. (Personal communication).Google Scholar
Cooper, B. (1961) Social class and prognosis in schizophrenia. British Journal of Preventive and Social Medicine, 15, 1741.Google ScholarPubMed
Depue, R. A. (1976) An activity-withdrawal distinction in schizophrenia: behavioural, clinical, brain damage and neurophysiological correlates. Journal of Abnormal Psychology, 55, 174–85.Google Scholar
Depue, R. A. & Dubicki, M. D. (1974) Hospitalization and premorbid characteristics in withdrawn and active schizophrenics. Journal of Consulting and Clinical Psychology, 42, 628–32.CrossRefGoogle ScholarPubMed
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 5763.Google Scholar
Fowler, R. C., McCabe, M. S., Cadoret, R. J. & Winokur, G. (1972) The validity of good prognosis schizophrenia. Archives of General Psychiatry, 26, 182–5.Google Scholar
Frith, C. D., Stevens, M., Johnstone, E. C. & Crow, T. J. (1978) Skin conductance responsivity during acute episodes of schizophrenia as a predictor of symptomatic improvement. Psychological Medicine, (in press).Google Scholar
Hawk, A. B., Carpenter, W. T. & Strauss, S. (1975) Diagnostic criteria and five-year outcome in schizophrenia. Archives of General Psychiatry, 32, 343–7.CrossRefGoogle ScholarPubMed
Johnstone, E. C., Crow, T. J., Frith, C. D., Carney, M. W. P. & Price, J. S. (1978) Mechanism of the antipsychotic effect in acute schizophrenia. Lancet, i, 848–51.Google Scholar
Kraepelin, E. (1919) Dementia Praecox and Paraphrenia. Translated by Mary Barclay, R. and Robertson, G. M., pp. 181–8; facsimile edition published by Krieger, New York, 1971.Google Scholar
Krawiecka, M., Goldberg, D. & Vaughan, M. (1977) A standardized psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatrica Scandinavica, 55, 299308.Google Scholar
Langfeldt, G. (1960) Diagnosis and prognosis of schizophrenia. Proceedings of the Royal Society of Medicine, 53, 1047–52.Google Scholar
Lilliston, L. (1973) Schizophrenic symptomatology as a function of probability of cerebral damage. Journal of Abnormal Psychology, 82, 377–81.Google Scholar
Mayer-Gross, W. (1932) Prognosis of schizophrenia. In Bumke's Handbuch der Geisteskrankheiten, 9, (5), pp. 534–6.Google Scholar
Romano, J. & Ebaugh, F. (1938) Prognosis in schizophrenia. American Journal of Psychiatry, 95, 583–96.Google Scholar
Schofield, W., Hathaway, S. R. et al (1954) Prognostic factors in schizophrenia. Journal of Consulting Psychology, 18, 155–66.Google Scholar
Strauss, J. S. & Carpenter, W. T. (1977) Prediction of outcome in schizophrenia. Archives of General Psychiatry, 34, 159–63.CrossRefGoogle ScholarPubMed
Vaillant, G. E. (1964) Prospective prediction of schizophrenic remission. Archives of General Psychiatry, 11, 509–18.CrossRefGoogle ScholarPubMed
Venables, P. H. (1957) A short scale for rating ‘Activity-Withdrawal’ in schizophrenics. Journal of Mental Science, 103, 197–9.Google Scholar
Warrington, E. K. (1974) Deficient recognition memory in organic amnesia. Cortex, 10, 289–91.CrossRefGoogle ScholarPubMed
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Description and Classification of Psychiatric Symptoms. An Instruction Manual for the PSE and Catego Systems. London: Cambridge University Press.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.