Hostname: page-component-6bf8c574d5-xtvcr Total loading time: 0 Render date: 2025-02-16T17:54:03.256Z Has data issue: false hasContentIssue false
  • English
  • Français

One Gene vs. Two Genes in Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Carol Buck
Carol Buck*
Affiliation:
University of Western Ontario, London, Ontario, Canada
Get access Rights & Permissions [Opens in a new window]

Extract

Arguments about the role of heredity in schizophrenia have largely given way to arguments about the genetic mechanisms involved. Discussions of the various genetic models by leading workers in the field have been presented in recent years (Rosenthal and Kety, 1968; Kaplan, 1972). Single gene theories have prevailed, Slater's intermediate model being preferred because of its good fit with the observed risks of schizophrenia in specific categories of blood relatives (Slater and Cowie, 1971).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 125 , Issue 587 , October 1974 , pp. 348 - 349
Copyright
Copyright © Royal College of Psychiatrists, 1974 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Kaplan, A. R., (ed.) (1972) Genetic Factors in Schizophrenia. Springfield, Ill.: G. C. Thomas.Google Scholar
Karlsson, J. L. (1966) The Biologic Basis of Schizophrenia. Springfield, Ill.: G. C. Thomas.Google Scholar
Karlsson, J. L. (1972) In Kaplan, op. cit. Google Scholar
Karlsson, J. L. (1973) An Icelandic family study of schizophrenia. Brit. J. Psychiat., 123, 549.CrossRefGoogle ScholarPubMed
Moran, P. A. P. (1972) In Kaplan, op. cit. Google Scholar
Oakes, M. W. (1968) Heterozygous advantage and its relation to heterozygote fetility. Ann. hum. Genet. Lond., 32, 173.Google Scholar
Rosenthal, D. & Kety, S. S. (1968) The Transmission of Schizophrenia. New York: Pergamon Press.Google Scholar
Slater, E. & Cowie, V. (1971) The Genetics of Mental Disorders. Oxford University Press.Google Scholar
Slater, E. (1972) In Kaplan, op. cit. Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.