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One Gene vs. Two Genes in Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Carol Buck
Carol Buck*
Affiliation:
University of Western Ontario, London, Ontario, Canada
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Extract

Arguments about the role of heredity in schizophrenia have largely given way to arguments about the genetic mechanisms involved. Discussions of the various genetic models by leading workers in the field have been presented in recent years (Rosenthal and Kety, 1968; Kaplan, 1972). Single gene theories have prevailed, Slater's intermediate model being preferred because of its good fit with the observed risks of schizophrenia in specific categories of blood relatives (Slater and Cowie, 1971).

Type
Research Article
Information
The British Journal of Psychiatry , Volume 125 , Issue 587 , October 1974 , pp. 348 - 349
Copyright
Copyright © Royal College of Psychiatrists, 1974 

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References

Kaplan, A. R., (ed.) (1972) Genetic Factors in Schizophrenia. Springfield, Ill.: G. C. Thomas.Google Scholar
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Rosenthal, D. & Kety, S. S. (1968) The Transmission of Schizophrenia. New York: Pergamon Press.Google Scholar
Slater, E. & Cowie, V. (1971) The Genetics of Mental Disorders. Oxford University Press.Google Scholar
Slater, E. (1972) In Kaplan, op. cit. Google Scholar
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