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Ocular Pigmentation, Extrapyramidal Symptoms and Phenothiazine Dosage

Published online by Cambridge University Press:  29 January 2018

R. H. Wheeler ,
V. R. Bhalerao  and
M. J. Gilkes
R. H. Wheeler
Affiliation:
St. Francis Hospital, Haywards Heath, Sussex
V. R. Bhalerao
Affiliation:
St. Francis Hospital, Haywards Heath, Sussex
M. J. Gilkes
Affiliation:
St. Francis Hospital, Haywards Heath, Sussex
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Extract

Oculo-cutaneous pigmentation has often been reported (Brit med. J., 1967) in patients receiving heavy doses of phenothiazines. This paper sets out to investigate, (a) the incidence of ocular pigmentation in such patients; (b) whether the measures suggested by Valentine and Jardine (1966) for minimizing this complication are effective; (c) the relationship of ocular pigmentation to extrapyramidal symptoms (and hence whether the pigmentation can be regarded as a sign of brain damage).

Type
Pharmacotherapy
Information
The British Journal of Psychiatry , Volume 115 , Issue 523 , June 1969 , pp. 687 - 690
Copyright
Copyright © Royal College of Psychiatrists, 1969 

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