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Nuclear Magnetic Resonance Brain Imaging in Chronic Schizophrenia

Published online by Cambridge University Press:  02 January 2018

J. A. O. Besson*
Affiliation:
Department of Mental Health, University of Aberdeen Clinical Research Centre
F. M. Corrigan
Affiliation:
Department of Mental Health, University of Aberdeen
G. R. Cherryman
Affiliation:
Aberdeen Royal Infirmary
F. W. Smith
Affiliation:
Aberdeen Royal Infirmary
*
Royal Cornhill Hospital, Cornhill Road, Aberdeen AB9 2ZH

Abstract

Patients with chronic schizophrenia were examined by nuclear magnetic resonance imaging of the brain. Subgroups of the syndrome with high positive or high negative symptom scores and ventricular dilatation were compared with each other and with normal controls in respect of regional spin lattice relaxation time (T1) changes. Significant differences were not observed between the schizophrenic subgroups and controls but there were significant differences between the subgroups themselves. The presence of tardive dyskinesia was associated with increased T1 of the basal ganglia. The significance of these results is discussed in relation to findings using other techniques.

Type
Research Article
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

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