Hostname: page-component-f554764f5-nqxm9 Total loading time: 0 Render date: 2025-04-10T17:46:31.323Z Has data issue: false hasContentIssue false
  • English
  • Français

Nuclear Magnetic Resonance Brain Imaging in Chronic Schizophrenia

Published online by Cambridge University Press:  02 January 2018

J. A. O. Besson ,
F. M. Corrigan ,
G. R. Cherryman  and
F. W. Smith
J. A. O. Besson*
Affiliation:
Department of Mental Health, University of Aberdeen Clinical Research Centre
F. M. Corrigan
Affiliation:
Department of Mental Health, University of Aberdeen
G. R. Cherryman
Affiliation:
Aberdeen Royal Infirmary
F. W. Smith
Affiliation:
Aberdeen Royal Infirmary
*
∗Royal Cornhill Hospital, Cornhill Road, Aberdeen AB9 2ZH
Get access Rights & Permissions [Opens in a new window]

Abstract

Patients with chronic schizophrenia were examined by nuclear magnetic resonance imaging of the brain. Subgroups of the syndrome with high positive or high negative symptom scores and ventricular dilatation were compared with each other and with normal controls in respect of regional spin lattice relaxation time (T1) changes. Significant differences were not observed between the schizophrenic subgroups and controls but there were significant differences between the subgroups themselves. The presence of tardive dyskinesia was associated with increased T1 of the basal ganglia. The significance of these results is discussed in relation to findings using other techniques.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 150 , Issue 2 , February 1987 , pp. 161 - 163
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

References

Benes, F., Sunderland, F., Jones, B. D., Le May, M., Cohen, B.M. & Lipinski, J. F. (1982) Normal ventricles in young schizophrenics. British Journal of Psychiatry, 141, 90–93.CrossRefGoogle ScholarPubMed
Besson, J. A. O., Corrigan, F. M., Foreman, E. I., Eastwood, L. M., Smith, F. W. & Ashcroft, G. W. (1985a) NMR imaging in dementia. British Journal of Psychiatry, 146, 31–35.CrossRefGoogle ScholarPubMed
Besson, J. A. O., Mutch, W. J., Downie, A. W., Smith, F. W., Corrigan, F. M., Ashcroft, G. W. & Crosher, G. A. (1985b) Das Verhältnis zwischen M. Parkinson und Demenzzustanden untersucht mithilfe von Protonen-NMR-Abbildungsparametern. Zeitschrift für Gerontologie, 18, 322–324.Google Scholar
Buchsbaum, M. S., Ingvon, D. H., Kessler, R., Waters, R. N., Cappelletti, J., Van Kammen, D. P., King, A. C., Jognson, J. L., Manning, R. G., Flynn, R. W., Mann, L. S., Bunney, W. E. & Sokoloff, L. (1982) Cerebral glucography with positron tomography. Archives of General Psychiatry, 39, 251–260.Google Scholar
Golden, C. J., Gräber, B., Coffman, J., Bag, R. A., Newlin, D. B. & Bloch, S. (1980) Structural brain deficits in schizophrenia. Archives of General Psychiatry, 38, 1014–1017.Google Scholar
Hutchison, J. M. S., Edelstein, S. A. & Johnson, G. (1980) A whole body NMR imaging machine. Journal of Physics E: Scientific Instruments, 13, 947–955.Google Scholar
Johnson, G., Hutchison, J. M. S. & Eastwood, L. M. (1981) Instrumentation for NMR spin warp imaging. Journal of Physics E: Scientific Instruments, 15, 74–79.Google Scholar
Johnstone, E. C., Crow, T. J., Firth, C. D., Husband, J. & Kreel, L. (1976) Cerebral ventricular size and cognitive impairment in schizophrenia. Lancet, ü, 924–926.Google Scholar
Krawiecka, M., Goldberg, D. & Vaughn, M. (1977) A standardised psychiatric assessment scale for rating chronic psychotic patients. Acta Psychiatrka Scandinavica, 55, 299–308.Google Scholar
Reveley, A. M., Reveley, M. A., Clifford, C. A. & Murray, R. M. (1982) Cerebral ventricular size in twins discordant for schizophrenia. Lancet, i, 540–541.Google Scholar
Reveley, A. M., Reveley, M. A., Clifford, C. A. & Murray, R. M. (1984) Cerebral ventricular enlargement in non-genetic schizophrenia: a twin study. British Journal of Psychiatry, 144, 89–93.Google Scholar
Trimble, M. R. & Kingsley, D. (1978) Cerebral ventricular size in chronic schizophrenia. Lancet, 1, 278–279.CrossRefGoogle ScholarPubMed
Weinberger, D. R., Torrey, E. F., Neophytes, A. N. & Wyatt, B. J. (1979) Lateral cerebral enlargement in chronic schizophrenia. Archives of General Psychiatry, 36, 735–739.CrossRefGoogle ScholarPubMed
Weinberger, D. R., Bigelow, L. B., Kleinman, J. E., Klein, S. T., Rosenblatt, J. E. & Wyatt, R. J. (1980) Cerebral ventricular enlargement in chronic schizophrenia. Archives of General Psychiatry, 37, 11–13.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.