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Neuroleptic Associated Tardive Dyskinesias in Young People with Psychoses

Published online by Cambridge University Press:  02 January 2018

Emmanuelle Pourcher ,
Philippe Baruch ,
Roch Hugo Bouchard ,
Marie-Josée Filteau  and
Danielle Bergeron
Emmanuelle Pourcher*
Affiliation:
Centre de Recherche Université Laval Robert-Giffard, Beauport (Québec), Canada
Philippe Baruch
Affiliation:
Centre de Recherche Université Laval Robert-Giffard, Beauport (Québec), Canada
Roch Hugo Bouchard
Affiliation:
Centre de Recherche Université Laval Robert-Giffard, Beauport (Québec), Canada
Marie-Josée Filteau
Affiliation:
Centre de Recherche Université Laval Robert-Giffard, Beauport (Québec), Canada
Danielle Bergeron
Affiliation:
Centre de Recherche Université Laval Robert-Giffard, Beauport (Québec), Canada
*
Dr Pourcher, Centre hospitalier Robert-Giffard, 2601, de la Canardière, Beauport (Qué.), G1J 2G3, Canada.
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Extract

Background

Apart from ageing, the factors associated with vulnerability to the emergence of tardive dyskinesia are poorly defined.

Method

Risk factors associated with the presence of a chronic choreic or dystonic disorder were assessed in a cross-sectional comparison of anamnestic and clinical data in a homogeneous group of 64 young psychotic patients (under 40 years of age) on chronic low to moderate doses of neuroleptics.

Results

Dyskinetic subjects presented more indirect indicators of occult brain damage, such as a perinatal event or traumatic brain injuries in infancy and early childhood; neurological examination showed more anomalies in dyskinetic patients than in non-dyskinetics, with a higher prevalence of facial release reflexes.

Conclusion

These data may support the hypothesis that occult acquired brain damage is important in the genesis of this ‘drug-induced’ disorder.

Type
Papers
Information
The British Journal of Psychiatry , Volume 166 , Issue 6 , June 1995 , pp. 768 - 772
Copyright
Copyright © Royal College of Psychiatrists, 1995 

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