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A Neuroendocrine Study of Stereotactic Sub-Caudate Tractotomy

Published online by Cambridge University Press:  29 January 2018

T. H. Corn ,
A. Honig ,
C. Thompson ,
P. K. Bridges ,
J. R. Bartlett  and
S. A. Checkley
T. H. Corn
Affiliation:
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF
A. Honig
Affiliation:
Geoffrey Knight Psychosurgical Unit, Brook General Hospital, Shooters Hill Road, London SE18 4IW
C. Thompson
Affiliation:
Institute of Psychiatry, London SE5 8AF
P. K. Bridges
Affiliation:
Geoffrey Knight Psychosurgical Unit, Brook General Hospital, London SE18 4IW
J. R. Bartlett
Affiliation:
Geoffrey Knight Psychosurgical Unit, Brook General Hospital, London SE18 4IW
S. A. Checkley
Affiliation:
The Maudsley Hospital, Denmark Hill, London SE5 8AZ
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Summary

The growth hormone and hypotensive responses to clonidine have been measured in six drug free severely depressed patients before, and at two weeks after, the surgical procedure of stereotactic sub-caudate tractotomy. The responses were unaltered two weeks after operation, by which time a small clinical improvement was evident. These findings are discussed in relation to central a adrenoceptor functions in depression, and the effect upon this of antidepressant treatment.

Type
Papers
Information
The British Journal of Psychiatry , Volume 144 , Issue 4 , April 1984 , pp. 417 - 420
Copyright
Copyright © 1984 The Royal College of Psychiatrists 

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