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Molecular Genetics and Human Disease Implications for Modern Psychiatric Research and Practice

Published online by Cambridge University Press:  02 January 2018

Miron Baron  and
John D. Rainer
Miron Baron*
Affiliation:
Division of Psychogenetics, Department of Medical Genetics, New York State Psychiatric Institute, and Associate Professor of Clinical Psychiatry, Columbia University College of Physicians and Surgeons
John D. Rainer
Affiliation:
Department of Medical Genetics, New York State Psychiatric Instituteand Professor of Clinical Psychiatry in Genetics and Development, Columbia University College of Physicians and Surgeons
*
∗Columbia University, College of Physicians and Surgeons, Department of Psychiatry, 722 West 168th Street, New York, NY 10032, USA
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Abstract

Techniques of molecular genetics, including recombinant-DNA technology, are likely to have a key role in modern psychiatric research and practice. This article reviews some methods of DNA analysis and their applications to clinical science: specifically, how these methods can be used to localise, identify, isolate, and clone clinically important genes, and how this should enable us to elucidate the molecular pathology of most inherited (psychiatric) disorders. The implications of these developments for prevention and treatment of genetic disease are discussed.

Type
Review Article
Information
The British Journal of Psychiatry , Volume 152 , Issue 6 , June 1988 , pp. 741 - 753
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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