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Mania Secondary to Procyclidine (‘Kemadrin’) Abuse

Published online by Cambridge University Press:  29 January 2018

Jeremy Coid  and
John Strang
Jeremy Coid
Affiliation:
The Bethlem Royal and Maudsley Hospital, Denmark Hill, London, SE5 8AZ
John Strang
Affiliation:
Manchester Drug Dependence Unit, Prestwich Hospital, Manchester, M25 7BL. Formerly Senior Registrar, Drug Dependence Clinical Research and Treatment Unit, The Bethlem Royal and Maudsley Hospital, London, SE5 8AZ
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Summary

A case of procyclidine abuse is described in which the clinical presentation was indistinguishable from mania. The patient was a long-standing poly-drug abuser and was obtaining the drugs from medical sources. Controlled exposure on the ward to drugs of abuse, including a double-blind comparison with placebo, confirmed that procyclidine caused a manic response in this patient.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 141 , Issue 1 , July 1982 , pp. 81 - 84
Copyright
Copyright © The Royal College of Psychiatrists 

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