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Manchester and Oxford Universities Scale for the Psychopathological Assessment of Dementia (MOUSEPAD)

Published online by Cambridge University Press:  02 January 2018

N. H. P. Allen*
Affiliation:
University of Manchester School of Psychiatry and Behavioural Sciences
Sheila Gordon
Affiliation:
University of Manchester School of Psychiatry and Behavioural Sciences
Tony Hope
Affiliation:
Department of Psychiatry, Warneford Hospital, Oxford
Alistair Burns
Affiliation:
University of Manchester School of Psychiatry and Behavioural Sciences
*
Dr N. H. P. Allen, Consultant Psychiatrist for the Elderly, Central Manchester Healthcare NHS Trust, Psychiatry Directorate, York House, York Place, Oxford Road, Manchester M13 9WL

Abstract

Background

There is increasing awareness of the importance of psychopathological and behavioural changes in dementia and a need for an instrument to measure these features which achieves an appropriate compromise between brevity and breadth. We describe a newly developed 59-item instrument: the MOUSEPAD.

Method

Reliability, sensitivity and validity were examined with 30 carers, each of whom was interviewed four times over six weeks.

Results

For different symptom groups, kappa ranged from 0.43 to 0.93 for test–retest reliability, from 0.56 to 1.0 for inter-rater reliability, and from 0.43 to 0.67 for the validation study.

Conclusions

The scale may be useful as an outcome measure in drug trials, for correlating psychopathological and behavioural changes with post-mortem findings, and in epidemiological surveys.

Type
Papers
Copyright
Copyright © 1996 The Royal College of Psychiatrists 

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References

Alexopoulos, G. S., Abrahams, R. C., Young, R. C., et al (1988) Cornell Scale for Depression in Dementia. Biological Psychiatry, 23, 271284.Google Scholar
Allen, N. H. P. & Burns, A. B. (1995) The non-cognitive features of dementia. Reviews in Clinical Gerontology, 5, 5775.Google Scholar
Bland, J. M. & Altman, D. G. (1986) Statistical methods for assessing agreement between two methods of clinical measurement Lancet, i, 307310.CrossRefGoogle Scholar
Burns, A. B., Jacoby, R. & Levy, R. (1990a) Psychiatric phenomena in Alzheimer's disease. I: Disorders of thought content British Journal of Psychiatry, 157, 7276.Google Scholar
Burns, A. B., Jacoby, R. & Levy, R. (1990b) Psychiatric phenomena in Alzheimer's disease. II: Disorders of perception. British Journal of Psychiatry, 157, 7681.Google Scholar
Burns, A. B., Jacoby, R. & Levy, R. (1990c) Psychiatric phenomena in Alzheimer's disease. III: Disorders of mood. British Journal of Psychiatry, 157, 8186.Google Scholar
Cummings, J. L., Mega, M., Gray, K., et al (1994) The Neuropsychiatric Inventory. Neurology, 44, 23082314.Google Scholar
Devanand, D. P., Brockington, C. D., Moody, B. J., et al (1992a) Behavioral syndromes in Alzheimer's disease. International Psychogeriatrics, 4 (suppl. 2), 161184.Google Scholar
Devanand, D. P., Miller, L., Richards, M., et al (1992b) The Columbia University Scale for Psychopathology in Alzheimer's Disease. Archives of Neurology, 49, 371376.CrossRefGoogle ScholarPubMed
Drevets, W. C. & Rubin, E. H. (1989) Psychotic symptoms and the longitudinal course of senile dementia of the Alzheimer type. Biological Psychiatry, 25, 3948.Google Scholar
Everitt, D. E., Fields, D. R., Soumerai, S. S., et al (1991) Resident behavior and staff distress in the nursing home. Journal of the American Geriatrics Society, 39, 792798.CrossRefGoogle ScholarPubMed
Fairburn, C. G. & Hope, R. A. (1988) Changes in eating in dementia. Neurobiology of Aging, 9, 2829.CrossRefGoogle ScholarPubMed
Förstl, H., Besthorn, C., Geiger-Kabisch, C., et al (1993) Psychotic features and the course of Alzheimer's disease: relationship to cognitive, electroencephalographic and computerized tomography findings. Acta Psychiatrica Scandinavica, 87, 395399.CrossRefGoogle ScholarPubMed
Hope, R. A. & Fairburn, C. G. (1990) The nature of wandering in dementia: a community-based study. International Journal of Geriatric Psychiatry, 5, 239245.Google Scholar
Hope, T. & Fairburn, C. G. (1992) The Present Behavioural Examination (BPE): the development of an interview to measure current behavioural abnormalities. Psychological Medicine, 22, 223230.Google Scholar
Hope, T., Tilling, K. M., Gedung, K., et al (1994) The structure of wandering in dementia. International Journal of Geriatric Psychiatry, 9, 149155.Google Scholar
Jeste, D. V., Wraog, R. E., Salmon, D. P., et al (1992) Cognitive deficits of patients with Alzheimer's disease with and without delusions. American Journal of Psychiatry, 149, 184189.Google Scholar
Landis, J. R. & Koch, G. G. (1977) The measurement of observer agreement for categorical data. Biometrics, 33, 159174.Google Scholar
Lopez, O. L., Becker, J. T., Brenner, R. P., et al (1991) Alzheimer's disease with delusions and hallucinations: neuropsychological and electroencephalographic correlates. Neurology, 41, 906912.Google Scholar
Margo, J. L., Robinson, J. R. & Corea, S. (1980) Referrals to a psychiatric service from old people's homes. British Journal of Psychiatry, 136, 396401.Google Scholar
Patterson, M. B., Schnell, A. H., Martin, R. L., et al (1990) Assessment of behavioral and affective symptoms in Alzheimer's disease. Journal of Geriatric Psychiatry and Neurology, 3, 2130.Google Scholar
Rabins, P. V., Mace, N. L. & Lucas, M. J. (1982) The impact of dementia on the family. Journal of the American Medical Association, 248, 333335.Google Scholar
Reisberg, B., Borenstein, J., Franssen, E., et al (1987) Behave-AD: A clinical rating scale for the assessment of pharmacologically remediable behavioral symptomatology in Alzheimer's disease. In Alzheimer's Disease. Problems, Prospects, and Perspectives (ed. Altman, H. J.), pp. 116. New York: Plenum Press.Google Scholar
Rosen, J. & Zubenko, G. S. (1991) Emergence of psychosis and depression in the longitudinal evaluation of Alzheimer's disease. Biological Psychiatry, 29, 224232.Google Scholar
Shrout, P. E., Spitzer, R. L. & Fleiss, J. L. (1987) Quantification of agreement in psychiatric diagnosis revisited. Archives of General Psychiatry, 44, 172177.Google Scholar
Steele, C., Rovner, B. W., Chase, G. A., et al (1990) Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease. American Journal of Psychiatry, 147, 10491051.Google Scholar
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Symptoms: An Instruction Manual for the PSE and CATEGO Programs. New York: Cambridge University Press.Google Scholar
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