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Lithium Neurotoxicity at Normal Therapeutic Levels

Published online by Cambridge University Press:  02 January 2018

A. J. Bell ,
A. Cole ,
D. Eccleston  and
I. N. Ferrier
A. J. Bell*
Affiliation:
University of Newcastle
A. Cole
Affiliation:
University of Newcastle
D. Eccleston
Affiliation:
University of Newcastle
I. N. Ferrier
Affiliation:
University of Newcastle, Department of Psychiatry, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP
*
∗ Correspondence
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Abstract

Four cases of lithium-induced neurotoxicity are presented which, taken with evidence from previous reports, indicate that specific risk factors for lithium-induced neurotoxicity at normal serum levels are rapid dosage regimes, concomitant neuroleptic therapy, pre-existing EEG abnormalities, undetected cerebral pathology, organic impairment, and genetic susceptibility.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 162 , Issue 5 , May 1993 , pp. 689 - 692
Copyright
Copyright © Royal College of Psychiatrists, 1993 

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