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A Linkage Study of Primary Affective Disorder

Published online by Cambridge University Press:  02 January 2018

Brent Waters ,
Dharmendra Sengar ,
Irene Marchenko ,
Gail Rock ,
Yvon Lapierre ,
Cynthia J. Forster-Gibson  and
Nancy E. Simpson
Brent Waters*
Affiliation:
Department of Child & Adolescent Psychiatry, Prince of Wales Hospital, New South Wales
Dharmendra Sengar
Affiliation:
Ottawa General Hospital
Irene Marchenko
Affiliation:
Formerly Royal Ottawa Hospital
Yvon Lapierre
Affiliation:
Royal Ottawa Hospital
Cynthia J. Forster-Gibson
Affiliation:
Queen's University, Kingston, Canada
Nancy E. Simpson
Affiliation:
Queen's University, Kingston, Canada
*
∗Department of Child and Adolescent Psychiatry, Prince of Wales Hospital, High Street, Randwick, New South Wales 2031, Australia
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Abstract

Marker loci in 113 members of nine unrelated multiplex families identified by a bipolar proband were tested for linkages with primary affective disorder. Linkage was excluded between the disease locus (assuming that it was a single autosomal dominant gene) and the HLA loci at a recombination fraction of 0.2, the ABO, Rh, and Lu loci at almost 0.05 and the Fy and P loci at 0.001.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 152 , Issue 4 , April 1988 , pp. 560 - 562
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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