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Iprindole and Imipramine in Non-Psychotic Depressed Out-Patients

Published online by Cambridge University Press:  29 January 2018

Karl Rickels ,
Hack R. Chung ,
Irma Csanalosi ,
Lester Sablosky  and
Joseph H. Simon
Karl Rickels
Affiliation:
University of Pennsylvania and Director of Psychopharmacology Research Unit
Hack R. Chung
Affiliation:
Philadelphia General Hospital, Philadelphia, Pennsylvania, U.S.A., 19104
Irma Csanalosi
Affiliation:
Philadelphia General Hospital, Philadelphia, Pennsylvania, U.S.A., 19104
Lester Sablosky
Affiliation:
Philadelphia General Hospital, Philadelphia, Pennsylvania, U.S.A., 19104
Joseph H. Simon
Affiliation:
Philadelphia General Hospital, Philadelphia, Pennsylvania, U.S.A., 19104
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Extract

In an earlier study this research group reported iprindole, a relatively new tricyclic derivative, to be an effective drug for use in depressed neurotic out-patients (ii). We found it to produce significantly greater improvement than placebo on a variety of outcome measures. Good response to iprindole as compared to placebo has also been reported by Hicks (5) and Daneman (3). Sterlin et al., comparing iprindole with amitriptyline in a relatively small patient sample, reported that iprindole, while faster acting, produced less overall improvement (15); differences in improvement did not, however, reach statistical significance.

Type
Papers
Information
The British Journal of Psychiatry , Volume 123 , Issue 574 , September 1973 , pp. 329 - 339
Copyright
Copyright © Royal College of Psychiatrists, 1973 

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References

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