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Implications of Adoption Studies on Schizophrenia
Published online by Cambridge University Press: 06 August 2018
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It is accepted that schizophrenia runs in families, but whether this relates to genetic or psychosocial transmission is an unanswered question. Kendler (1988) has articulated four testable hypotheses: (a) a general liability to any psychiatric illness (b) a liability to schizotypal functioning — oddness, suspiciousness etc. (c) a liability to broadly defined schizophrenic psychosis, or any functional, non-affective psychosis and (d) a specific liability to narrowly defined schizophrenia, e.g. using DSM-III-R criteria (American Psychiatric Association, 1987). Kendler suggests that neither hypothesis (a) nor (d) is correct, and that the familial predisposition is neither completely non-specific nor highly specific; available results strongly support the second hypothesis and also provide some support in favour of the third.
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