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HLA Antigens in Schizophrenia: No Difference Between Patients with and Without Evidence of Brain Atrophy

Published online by Cambridge University Press:  29 January 2018

Elias Frangos ,
Nitsa Renieri-Livieratou ,
George Athanassenas ,
Ekaterini Stavropoulou-Ghioka  and
Antony Kourkoubas
Elias Frangos
Affiliation:
3rd Department of Psychiatry, State Mental Hospital of Athens, Daphni, Greece
Nitsa Renieri-Livieratou
Affiliation:
Tissue Typing Laboratory, General Hospital of Athens, Greece
George Athanassenas
Affiliation:
3rd Department of Psychiatry, State Mental Hospital of Athens, Daphni, Greece
Ekaterini Stavropoulou-Ghioka
Affiliation:
Tissue Typing Laboratory, General Hospital of Athens, Greece
Antony Kourkoubas
Affiliation:
3rd Department of Psychiatry, State Mental Hospital of Athens, Daphni, Greece
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Summary

The HLA antigens distribution was studied in 56 chronic schizophrenic in-patients with or without brain atrophy determined by CAT examination, and compared with that of 200 controls. There was no difference in the incidence of HLA-A2 in the whole sample, and an increase in those without brain atrophy (by comparison with normal controls) failed to reach statistical significance. A decrease of Bw35 in the whole sample, more prominent in those without brain atrophy, again failed to be significant after multiplying the probability by the number of antigens studied.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 140 , Issue 6 , June 1982 , pp. 607 - 610
Copyright
Copyright © Royal College of Psychiatrists, 1982 

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