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Growth Hormone After Trh in Women with Depressive Illness

Published online by Cambridge University Press:  29 January 2018

P. Linkowski
Affiliation:
Department of Psychiatry, Hôpital Erasme, Free University of Brussels
H. Brauman
Affiliation:
Laboratory of Clinical Biology, Hôpital Brugmann, Free University of Brussels
J. Mendlewicz
Affiliation:
Hôpital Erasme, Free University of Brussels, 808 route de Lennick, 1070 Brussels, Belgium

Summary

Plasma growth hormone (GH) release after TRH injection was investigated in 27 unipolar and 23 bipolar depressive women, and in 39 normal female controls matched for age, sex and menopausal status. Peaks of GH secretion after TRH were observed in some depressive patients as well as in some normal controls, but there were no significant differences in GH response after TRH administration between patients and controls. The implications of these findings are discussed in reference to such factors as non-specific stress responses and abnormal neuroendocrine circadian rhythms in affectively ill patients.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1980 

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