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Genetic Implications in Assortative Mating of Affective Disorders

Published online by Cambridge University Press:  29 January 2018

Enrico Smeraldi ,
Fiammetta Negri ,
Anna Maria Melica ,
Rosanna Zuliani ,
Mariangela Gasperini  and
F. Macciardi
Enrico Smeraldi*
Affiliation:
Institute of Clinical Psychiatry; Milan University School of Medicine, via F. Sforza 35, 20122 Milan, Italy
Fiammetta Negri
Affiliation:
Institute of Clinical Psychiatry; Milan University School of Medicine, via F. Sforza 35, 20122 Milan, Italy
Anna Maria Melica
Affiliation:
Institute of Clinical Psychiatry; Milan University School of Medicine, via F. Sforza 35, 20122 Milan, Italy
Rosanna Zuliani
Affiliation:
Institute of Clinical Psychiatry; Milan University School of Medicine, via F. Sforza 35, 20122 Milan, Italy
Mariangela Gasperini
Affiliation:
Institute of Clinical Psychiatry; Milan University School of Medicine, via F. Sforza 35, 20122 Milan, Italy
F. Macciardi
Affiliation:
Institute of Clinical Psychiatry; Milan University School of Medicine, via F. Sforza 35, 20122 Milan, Italy
*
∗ Correspondence.
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Summary

Psychiatric disorders in a sample of spouses of probands with recurrent Primary Affective Disorders (PAD) and in their first degree relatives were evaluated and compared with those in the spouses of control subjects without psychiatric illnesses. No differences were found in the risk for PAD, but spouses of PAD patients and their respective first degree relatives manifested a greater incidence of affective spectrum disorders.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 138 , Issue 3 , March 1981 , pp. 236 - 239
Copyright
Copyright © Royal College of Psychiatrists, 1981 

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References

Andreasen, N. C. & Winokur, G. (1979) Newer experimental methods for classifying depression. Archives of General Psychiatry, 36, 447–452.Google Scholar
Bodmer, W. F. & Cavalli-Sforza, L. L. (1971) The Genetics of Human Population. San Francisco: Freeman Publications.Google Scholar
Cloninger, R. C. Rice, J. & Reich, T. (1979) Multifactorial inheritance with cultural transmission and assortative mating—II. A general model of combined polygenic and cultural inheritance. American Journal of Human Genetics, 31, 176–198.Google Scholar
Crowe, R. R. & Smouse, P. E. (1977) The genetic implications of age-dependent penetrance in manic-depressive illness. Journal of Psychiatric Research, 13, 273–285.Google Scholar
Dunner, D. L. Fleiss, J. L. Addonizio, G. & Fieve, R. R. (1976) Assortative mating in primary affective disorders. Biological Psychiatry, 11, 43–51.Google Scholar
Gershon, E. S. Dunner, D. L. Sturt, L. & Goodwin, F. K. (1973) Assortative mating in the affective disorders. Biological Psychiatry, 7, 63–74.Google Scholar
Gershon, E. S. Mark, A. Cohen, N. B. Baron, M. & Knobe, E. (1975a) Transmitted factors in the morbid risk of affective disorders—a controlled study. Journal of Psychiatric Research, 12, 283–299.Google Scholar
Gershon, E. S. Baron, M. & Leckman, J. F. (1975b) Genetic models of the transmission of affective disorders. Journal of Psychiatric Research, 12, 301–317.Google Scholar
Gershon, E. S. Targum, S. D. Kessler, L. R. Mazure, C. M. & Bunney, W. E Jr . (1977) Genetic studies and biological strategies in the affective disorders. Progress in Medical Genetics, New Series, 101–164.Google Scholar
Green, R. Goetzl, V. & Whybrow, P. C. (1973) X-linked transmission of manic-depressive illness. Journal of the American Medical Association, 223, 1289.Google Scholar
Mendlewicz, J. Fieve, R. R. Rainer, J. D. & Cataldo, M. (1973) Affective disorder of paternal and maternal sides—observations in bipolar (manic-depressive) patients with and without a family history. British Journal of Psychiatry, 122, 31–34.Google Scholar
Negri, F. Melica, A. M. Zuliani, R. & Smeraldi, E. (1979) Assortative mating and affective disorders. Journal of Affective Disorders, 1, 247–253.CrossRefGoogle ScholarPubMed
Perris, C. (1971) Abnormality on paternal and maternal sides—observation in bipolar (manic-depressive) and unipolar depressive psychoses. British Journal of Psychiatry, 118, 207–210.Google Scholar
Slater, E. Maxwell, J. & Price, J. S. (1971) Distribution of ancestral secondary cases in bipolar affective disorders. British Journal of Psychiatry, 118, 215–218.Google Scholar
Smeraldi, E. Negri, F. & Melica, A. M. (1977) A genetic study of affective disorders. Acta Psychiatrica Scandinavica, 56, 382–398.Google Scholar
Smeraldi, E. Kidd, K. K. Negri, F. Heimbuch, R. & Melica, A. M. (1979) Genetic studies of affective disorders. In Biological Psychiatry Today (eds. J. Obiols, C. Ballus, E. Gonzales Monclus and J. Pujol), pp 60–65. Amsterdam: Elsevier.Google Scholar
Spitzer, R. L. Endicott, J. & Robins, E. (1978) Research diagnostic criteria. Archives of General Psychiatry, 35, 773–782.Google Scholar
Von Grieff, H. McHugh, P. R. & Stokes, P. E. (1973) The familial history in sixteen males with bipolar manic-depressive disorder. Paper presented at 63rd Annual Meeting of American Psychopathological Association, New York.Google Scholar
Wilson, S. R. (1978) A note on assortative mating, linkage and genotypic frequencies. Annals of Human Genetics, 42, 129–130.Google Scholar
Winokur, G. Cadoret, R. Dorzab, J. & Baker, M. (1971) Depressive disease—a genetic study. Archives of General Psychiatry, 24, 135–144.Google Scholar
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