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Fluctuations in Schizophrenic Births by Year

Published online by Cambridge University Press:  02 January 2018

E. Fuller Torrey  and
Robert R. Rawlings
E. Fuller Torrey*
Affiliation:
National Institute of Mental Health, Neuroscience Center at St Elizabeths, Washington, DC 20032
Robert R. Rawlings
Affiliation:
National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
*
Dr E Fuller Torrey, Dept. Of Health & Human Services, NIMH Neuropsychiatric Research Hospital, 2700 Martin Luther King Jr Ave. SE, Washington, DC 20032, USA
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Abstract

Background

It has previously been reported that births of individuals who later develop schizophrenia vary by birth year.

Method

Birth data were analysed on 34 024 individuals diagnosed with DSM–III–R disorganised, catatonic, and undifferentiated schizophrenia using time series analysis.

Results

Minor yearly fluctuations were observed but did not achieve statistical significance. Thus earlier findings reported in the literature could not be replicated using a different statistical approach.

Conclusion

The findings do not support theories which assume major yearly fluctuations in the births of individuals with schizophrenia. Such theories include the perinatal effects of influenza, temperature variation, and the effects of severe weather.

Type
Papers
Information
The British Journal of Psychiatry , Volume 169 , Issue 6 , December 1996 , pp. 772 - 775
Copyright
Copyright © 1996 The Royal College of Psychiatrists 

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References

Box, G. & Jenkins, G. (1976) Time Series Analysis: Forecasting and Control. San Francisco: Holden-Day.Google Scholar
Boyd, J. H., Pulver, A. E. & Stewart, W. (1986) Season of birth: Schizophrenia and bipolar disorder. Schizophrenia Bulletin, 12, 173–185.CrossRefGoogle ScholarPubMed
Bradbury, T. N. & Miller, G. A. (1985) Season of birth in schizophrenia: A review of evidence, methodology, and etiology. Psychological Bulletin, 98, 569–594.Google Scholar
Frome, E., Kutner, M. & Beauchamp, J. (1973) Regression analysis of Poisson-distributed data. Journal of the American Statistical Association, 68, 935–959.Google Scholar
Johnson, N. L. & Katz, S. (1969) Discrete Distributions. New York: Wiley.Google Scholar
Kendell, R. E. & Adams, W. (1991) Unexplained fluctuations in the risk for schizophrenia by month and year of birth. British Journal of Psychiatry, 158, 758–763.Google Scholar
Kinney, D., Waternaux, C., Spivak, C., et al (1993) Schizophrenia risk predicted by meteorological events near birth. Abstract. Schizophrenia Research, 9, 135.CrossRefGoogle Scholar
Mednick, S. A., Huttenen, M. O. & Machon, R. A. (1994) Prenatal influenza infections and adult schizophrenia. Schizophrenia Bulletin, 20, 263–267.CrossRefGoogle ScholarPubMed
Sham, P. C., O'Callaghan, E. O., Takei, N., et al (1992) Schizophrenia following pre-natal exposure to influenza epidemics between 1939 and 1960. British Journal of Psychiatry, 160, 461–467.Google Scholar
Statsoft, Inc (1995) Statistica for Windows, Tulsa.Google Scholar
Welham, J. L., McLachlin, J. & McGrath, J. J. (1994) Implications of an irregular seasonal effect in schizophrenia birth rates. Abstract Schizophrenia Research, 11, 101.Google Scholar
Youssef, H. A., Kinsella, A. & Waddington, J. L. (1994) Space–time clustering in the births of schizophrenic patients and its relationship to familial morbid risk. Abstract Schizophrenia Research, 11, 101.Google Scholar
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