Hostname: page-component-cd9895bd7-q99xh Total loading time: 0 Render date: 2024-12-22T16:33:57.106Z Has data issue: false hasContentIssue false
  • English
  • Français

Failure to Replicate Evoked Potential Observations Suggesting Corpus Callosum Dysfunction in Schizophrenia

Published online by Cambridge University Press:  29 January 2018

Charles Shagass ,
Richard C. Josiassen ,
Richard A. Roemer ,
John J. Straumanis  and
Stephen M. Slepner
Charles Shagass
Affiliation:
Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.A.
Richard C. Josiassen
Affiliation:
Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.A.
Richard A. Roemer
Affiliation:
Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.A.
John J. Straumanis
Affiliation:
Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.A.
Stephen M. Slepner
Affiliation:
Temple University Medical School and Eastern Pennsylvania Psychiatric Institute, Philadelphia PA 19129, U.S.A.
Get access Rights & Permissions [Opens in a new window]

Summary

Somatosensory potentials (SEPs) evoked by vibrotactile finger stimulation have been reported to be the same in both hemispheres in schizophrenics, whereas they are asymmetrical in normals, with the contralateral hemisphere leading the ipsilateral (Jones and Miller, 1981). These findings were taken to indicate that the corpus callosum is nonfunctional in schizophrenics. To attempt replication of these results, vibrotactile SEPs of 6 schizophrenics and 6 normal controls were recorded with both bipolar and monopolar derivations. Assymetrical bipolar SEPs were obtained in both schizophrenics and controls; previous observations of schizophrenic-control differences were not replicated. Acceptable evidence of ipsilateral early SEPs was not obtained; the test procedure seems inappropriate for measuring callosal conduction time.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 142 , Issue 5 , May 1983 , pp. 471 - 476
Copyright
Copyright © 1983 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association (1980) Diagnostic and Statistical Manual of Mental Disorders. Google Scholar
Connolly, J. F. (1982) Correspondence. British Journal of Psychiatry, 140, 429–30.Google Scholar
Desmedt, J. E. & Brunko, , (1980) Functional organization of far-field and cortical components of somatosensory evoked potentials in normal adults. In Clinical Uses of Cerebral Brainstem and Spinal Somatosensory Evoked Potentials. Progress in Clinical Neurophysiology, 27–50, Vol. 7. (ed. Desmedt, J. E.). Basel: Karger.Google Scholar
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.Google Scholar
Jasper, H. H. (1958) The ten twenty electrode system of the International Federation. Electroencephalography and Clinical Neurophysiology, 10, 371–5.Google Scholar
Jones, G. H. & Miller, J. J. (1981) Functional tests of the corpus callosum in schizophrenia. British Journal of Psychiatry, 139, 553–7.Google Scholar
Pandya, D. N. & Vignolo, L. A. (1969) Interhemispheric projections of the parietal lobe in the rhesus monkey. Brain Research, 15, 49–65.Google Scholar
Salamy, A. (1978) Commissural transmission: maturational changes in humans. Science, 200, 1409–11.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.