Hostname: page-component-586b7cd67f-t7fkt Total loading time: 0 Render date: 2024-11-22T07:51:59.533Z Has data issue: false hasContentIssue false

Effects of Serum from Schizophrenics on Evoked Cortical Potentials in the Rat

Published online by Cambridge University Press:  29 January 2018

G. A. German*
Affiliation:
University of Aberdeen, and Psychiatry, Ross Clinic, Aberdeen

Extract

Many experiments have been reported suggesting that the serum of schizophrenic patients differs in some way from the serum of non-schizophrenic subjects, either in respect of some specific constituent or of the alterations in function which it can produce when added to various biological systems (Heath, 1957; Walaszek, 1960; Bergen, Koella, Czicman and Hoagland, 1961). These reports suggest that schizophrenia is a pathological mental condition resulting from some disorder of metabolism or of biochemical processes, and it would be logical to expect that this disorder would be most manifest as a disturbance of the neurological activity in the cerebrum—perhaps more specifically in the cerebral cortex—since the clinical picture in schizophrenia is primarily one of gross derangement of the processes of perception, attention and thinking.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1963 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bergen, J. R. Koella, W. P. Czicman, J. and Hoagland, H. (1961). Fed. Proc., 20, 305.Google Scholar
Craigie, E. H. (1925). An Introduction to the Finer Anatomy of the Nervous System based upon that of the Albino Rat. p. 111. Toronto: University of Toronto Press.Google Scholar
Galambos, R. (1961). Fed. Proc., 20, 603608.Google Scholar
Heath, R. (1957). Neuropharmacology, 4, 37151.Google Scholar
Hoffer, A. and Osmond, H. (1960). The Chemical Basis of Clinical Psychiatry. p. 125. Springfield: Thomas.Google Scholar
Kanai, T. Misrahy, G. and Clark, L. C. (1962). Fed. Proc., 21, 322.Google Scholar
Merlis, J. K. (1940). Amer. J. Physiol., 131, 6772.Google Scholar
Payne, R. W. Mattussek, P. and George, E. I. (1959). J. ment. Sci., 105, 627652.Google Scholar
Rovetta, P. (1956). Electroenceph. clin. Neurophysiol., 8, 1524.Google Scholar
Walaszek, E. J. (1960). Int. Rev. Neurobiol., 2, 137173.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.