Hostname: page-component-848d4c4894-tn8tq Total loading time: 0 Render date: 2024-07-07T20:22:25.508Z Has data issue: false hasContentIssue false
  • English
  • Français

The Effect of Parachlorophenylalanine on the Sleep of a Methadone Addict

Published online by Cambridge University Press:  29 January 2018

D. A. Chernik ,
J. Mendels  and
T. A. Ramsey
D. A. Chernik
Affiliation:
Sleep Laboratory
J. Mendels
Affiliation:
Depression Research Unit, University of Pennsylvania Department of Psychiatry, V.A. Hospital, University and Woodland Avenues, Philadelphia, Pennsylvania, 19104, U.S.A.
T. A. Ramsey
Affiliation:
Center for the Study of Narcotic and Drug Abuse, National Institute of Mental Health, Rockville, Maryland 20852, U.S.A.
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Other
Information
The British Journal of Psychiatry , Volume 122 , Issue 567 , February 1973 , pp. 191 - 197
Copyright
Copyright © Royal College of Psychiatrists, 1973 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baekeland, F., and Lasky, R. (1966). ‘Exercise and sleep patterns in college athletes.’ Perceptual and Motor Skills, 23, 1203.Google Scholar
Caldwell, D. F., and Domino, E. F. (1967). ‘Electroencephalographic and eye movement patterns during sleep in chronic schizophrenic patients. Electroencephalographic and Clinical Neurophysiology, 22, 414.CrossRefGoogle ScholarPubMed
Cohen, H. B., Ferguson, J. M., Henriksen, S. J., Stolk, J. M., Zarcone, V. J., Barchas, J. D., and Dement, W. C. (1970). ‘Effects of chronic depletion of brain serotonin on sleep and behaviour.’ Proceedings, 78th Annual Convention of American Psychological Association, 831–2.Google Scholar
Delorme, F., Froment, F., and Jouvet, M. (1966). ‘Suppression du sommeil per la p-chloromethamphctamine et la p-chlorophenylalanine.’ Comptes-Rendus des Séances de la Société de Biologie (Paris), 160, 2347–51.Google Scholar
Engelman, K. (1970). ‘Malignant carcinoid syndrome.’ Annals of Internal Medicine, 73, 611–3.Google Scholar
Feinberg, I., Braun, M., Koresko, R. L., and Gottlieb, F. (1969). ‘Stage 4 sleep in schizophrenia.’ Archives of General Psychiatry, 21, 262.Google Scholar
Ferguson, J., Cohen, H., Henricksen, S., McGarr, K., Mitchell, G., Hoyt, G., Barchas, J., and Dement, W. C. (1969). ‘The effect of chronic administration of parachlorophenylalanine on sleep in the cat.’ Psychophysiology, 6(2), 220–1 (abstract).Google Scholar
Florio, V., Scotti DeCarolis, A. S., and Longo, V. G. (1968). ‘Observations on the effect of DL-parachlorophenylalanine on the electroencephalogram.’ Physiology and Behavior, 3, 861–3.Google Scholar
Gresham, S., Agnew, H., and Williams, R. (1965). ‘The sleep of depressed patients.’ Archives of General Psychiatry, 12, 503–7.Google Scholar
Griffiths, W. J., Lester, B. K., Coulter, J. D., and Williams, H. L. (1971). ‘Tryptophan and sleep in young adults.’ Psychophysiology. In press.Google Scholar
Henderson, A., Nemes, G., Gordon, N. B., and Roos, L. (1970). ‘Sleep and narcotic tolerance.’ Psychophysiology, 7, 346–7 (abstract).Google Scholar
Heuser, G., Kales, A., Jacobson, A., Paulson, M. J., Zweizig, J. R., Walter, R. D., and Kales, J. D. (1966). ‘Sleep patterns in hypothyroid patients.’ Physiologist, 9.Google Scholar
Hobson, J. A. (1968). ‘Sleep after exercise.’ Science, 162, 1503.CrossRefGoogle ScholarPubMed
Jequier, E., Lovenberg, W., and Sjoerdsma, A. (1967). ‘Tryptophan hydroxylase inhibition: The mechanism by which p-chlorophenylalanine depletes rat brain serotonin.’ Molecular Pharmacology, 3, 274–8.Google Scholar
Jouvet, M. (1967). ‘Mechanisms of the states of sleep. A neuropharmacological approach’, in Sleep and Altered States of Consciousness (eds. S. S. Kety, E. V. Evarts and H. L. Williams), pp. 88–126. Baltimore: Williams and Wilkins.Google Scholar
Kales, A., Beall, G. N., Berger, R. J., Heuser, G., Jacobson, A., Kales, J. D., Parmelee, A. H., and Walter, R. D. (1968). ‘Sleep and dreams: Recent research on clinical aspects.’ Annals of Internal Medicine, 65, 1078.Google Scholar
Karacan, I., Heine, M., Agnew, H. W., Williams, R. L., Webb, W. B., and Ross, J. J. (1968). ‘Characteristics of sleep patterns during late pregnancy and the postpartum periods.’ American Journal of Obstetrics and Gynaecology, 101, 579.Google Scholar
Karadzic, V. (1968). ‘Para-chlorophenylalanine and sleep in cats.’ Archiv. Biol. Nauka, 20, 27–31 (Transi. 1970).Google Scholar
Kay, D. C., and Martin, W. R. (June 1971). ‘Human sleep during a chronic methadone cycle.’ Paper presented at the meeting of the Association for the Psychophysiological Study of Sleep, Belgium.Google Scholar
Koe, B. F. (1971). ‘Tryptophan hydroxylase inhibitors.’ Federation Proceedings, 30, 886–96.Google Scholar
Koella, W. P. (1969). ‘Neurohumoral aspects of sleep control.’ Biological Psychiatry, 1, 161–77.Google Scholar
Koella, W. P., Feldstein, A., and Czicman, J. S. (1968). ‘The effect of para-chlorophenylalanine on the sleep of cats.’ Electroencephalography and Clinical Neurophysiology, 25, 481–90.Google Scholar
Korf, J., Valkenburoh-Sikkema, T. (1969). ‘Fluorometric determination of 5-hydroxyindoleacetic acid in human urine and cerebrospinal fluid.’ Clinica Chimica Acta, 26, 301–6.Google Scholar
Lowy, F. H., Cleoborn, J. M., and McClure, D. J. (1971). ‘Sleep patterns in depression.’ Journal of Nervous and Mental Diseases, 153, 10–26.Google Scholar
Mandell, M. P., Mandell, A. J., and Jacobson, A. (1964). ‘Biochemical and neurophysiological studies of paradoxical sleep.’ Recent Advances in Biological Psychiatry, 7, 115–22.Google Scholar
Mendels, J., and Hawkins, D. R. (1967a). ‘Sleep and depression: A controlled EEG study.’ Archives of General Psychiatry, 16, 344–54.Google Scholar
Mendels, J., and Hawkins, D. R. (1967b). ‘Sleep and depression: A follow-up study.’ Archives of General Psychiatry, 16, 536–42.Google Scholar
Mendels, J., and Hawkins, D. R. (1972). ‘Sleep studies in depression’, in Recent Advances in the Psychobiology of the Depressive Illness (eds. W. T. Katz, and J. A. Shields), pp. 145–67. Washington, D.C.: Government Printing.Google Scholar
Mouret, J., Bobillier, P., and Jouvet, M. (1968). ‘Insomnia following para-chlorophenylalanine in the rat.’ European Journal of Pharmacology, 5, 17–22.Google Scholar
Rechtschaffen, A., and Kales, A. (1968). A Manual of Standardized Terminology, Techniques, and Scoring System for Sleep Stages of Human Subjects. U.S. Public Health Service, Washington, D.C.: U.S. Government Printing Office.Google Scholar
Rechtschaffen, A., Lovell, R., Freedman, D., Whitehead, P., and Aldrich, M. (1969). ‘Effect of para-chlorophenylalanine on sleep in rats.’ Psychophysiology, 6, 223.Google Scholar
Rechtschaffen, A., Michel, F., and Metz, J. T. (June 1971). ‘Relationship between extraocular and PGO activity in the cat.’ Paper presented at the meeting of the Association for the Psychophysiological Study of Sleep, Belgium.Google Scholar
Rechtschaffen, A., Molinari, S., Watson, R., and Wincor, M. Z. (1971). ‘Extraocular potentials: A possible indication of PGO activity in the human.’ Psychophysiology, 7, 336.Google Scholar
Snyder, F. (1968). ‘Electrographic studies of sleep in depression’, in Computers and Electronic Devices in Psychiatry (eds. N. S. Kline, and E. Laske), p. 272. New York: Grune and Stratton.Google Scholar
Tenen, S. S. (1968). ‘Antagonism of the analgesic effect of morphine and other drugs by p-chlorophenylalanine, a serotonin depletor.’ Psychopharmacologia, 12, 278–85.Google Scholar
Torda, G. (1969). ‘Biochemical and bioelectric processes related to sleep, paradoxal sleep and arousal.’ Psychology Reports, 24, 807.Google Scholar
Way, E. L., Loh, H. H., and Shen, F. (1968). ‘Morphine tolerance, physical dependence and synthesis of brain 5-hydroxytryptamine.’ Science, 162, 1290–2.Google Scholar
Williams, H. L. (1971). ‘The new biology of sleep.’ Journal of Psychiatric Research, 8, 445–78.Google Scholar
Wyatt, R. J., Chase, T. N., Engelman, K., Kupfer, D. J., Scott, J., Sjoerdsma, A., and Snyder, F. (1970). ‘Reversal of para-chlorophenylalanine (PCPA) REM suppression in man by 5-hydroxytryptophan (5-HTP).’ Psychophysiology, 7(2), 318–9 (abstract).Google Scholar
Wyatt, R. J., Engelman, K., Kupfer, D. J., Fram, D. H., Sjoerdsma, A., and Snyder, F. (1970). ‘Effect of L-tryptophan (a natural sedative) on human sleep.’ Lancet, ii, 842–6.Google Scholar
Wyatt, R. J., Kupfer, D. J., Scott, J., Sjoerdsma, A., and Snyder, F. (1969). ‘Effects of para-chlorophenylalanine on sleep in man.’ Electroencephalography and Clinical Neurophysiology, 27, 529–32.CrossRefGoogle ScholarPubMed
Wyatt, R. J., Gillin, J. C., Green, R., Horwitz, D., and Snyder, F. (June 1971). ‘Measurement of phasic integrated potentials (PIP) during treatment with para-chlorophenylalanine (PCPA).’ Paper presented at the meeting of the Association for the Psychophysiological Study of Sleep, Belgium.Google Scholar
Wyatt, F. J., Zarcone, V., Engelman, K., Dement, W. C., Snyder, F., and Sjoerdsma, A. (1971). ‘Effects of 5-hydroxytryptophan on the sleep of normal human subjects.’ Electroencephalography and Clinical Neurophysiology, 30, 505–9.Google Scholar
Zung, W. W. K., Wilson, W. P., and Dodson, W. E. (1964). ‘Effects of depressive disorders on sleep EEG responses.’ Archives of General Psychiatry, 10, 439.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.