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A Double-Blind Trial of Intravenous Thyrotrophin-Releasing Hormone in the Treatment of Reactive Depression

Published online by Cambridge University Press:  29 January 2018

L. E. J. Evans ,
P. Hunter ,
R. Hall ,
Moira Johnston  and
V. Mathew Roy
L. E. J. Evans
Affiliation:
Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP
P. Hunter
Affiliation:
Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP (Royal Salop Infirmary, Shrewsbury)
R. Hall
Affiliation:
University of Newcastle upon Tyne, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LD
Moira Johnston
Affiliation:
Royal Victoria Infirmary, Newcastle upon Tyne
V. Mathew Roy
Affiliation:
Department of Medicine, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP (Medical College Hospital, Trivandrum 11, Kerala, India)
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Summary

In a double-blind trial 600 μg. of thyrotrophin-releasing hormone (TRH) was compared with placebo given daily for four days to two groups of ten patients. There was no significant difference between the antidepressant effects of TRH and placebo.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 127 , Issue 3 , September 1975 , pp. 227 - 230
Copyright
Copyright © Royal College of Psychiatrists, 1975 

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Footnotes

present address: St. Nicholas Hospital, Gosforth, Newcastle upon Tyne, NE3 3XT

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