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Double-Blind Study of Imipramine versus Phenelzine in Melancholias and Dysthymic Disorders

Published online by Cambridge University Press:  02 January 2018

J. Vallejo ,
C. Gasto ,
R. Catalan  and
M. Salamero
J. Vallejo*
Affiliation:
Department of Psychiatry, University Hospital, University of Barcelona
C. Gasto
Affiliation:
Department of Psychiatry, University Hospital, University of Barcelona
R. Catalan
Affiliation:
Department of Psychiatry, University Hospital, University of Barcelona
M. Salamero
Affiliation:
Department of Psychiatry, University Hospital, University of Barcelona
*
∗Department of Psychiatry, University Hospital, University of Barcelona
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Abstract

In a 6-week double-blind trial, the efficacy of imipramine and high dose phenelzine were compared in the treatment of Major Depression with Melancholia, and Dysthymic Disorder (DSM-III). Both drugs were found to be equally efficacious in the treatment of 32 patients suffering from Major Depression. In 32 Dysthymic patients, phenelzine in high doses was found to be superior to imipramine. The clinical implications of these findings are discussed.

Type
Papers
Information
The British Journal of Psychiatry , Volume 151 , Issue 5 , November 1987 , pp. 639 - 642
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

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