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A Double-Blind Out-Patient Trial of Indalpine vs Mianserin

Published online by Cambridge University Press:  29 January 2018

G. J. Naylor  and
B. Martin
G. J. Naylor*
Affiliation:
The Department of Psychiatry University of Dundee, Dundee DD1 9SY, Scotland
B. Martin
Affiliation:
Royal Dundee Liff Hospital, Dundee DD2 5NF, Scotland
*
∗Correspondence
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Summary

Indalpine 150 mg per day and mianserin 60 mg per day were compared in a double-blind study of 65 depressed out-patients: 52 patients completed the 4-week trial. At the end of four weeks there was no significant difference in antidepressant effect between the two drugs; but in the first two weeks, improvement in the mianserin-treated group was significantly greater than that in the indalpine group. The mianserin-treated group reported more side-effects of sedation (eg. drowsiness, clumsiness, heaviness of limbs etc.) and one patient on indalpine developed a mild leucopenia.

Type
Papers
Information
The British Journal of Psychiatry , Volume 147 , Issue 3 , September 1985 , pp. 306 - 309
Copyright
Copyright © 1985 The Royal College of Psychiatrists 

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