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A Double-Blind Controlled Trial of a Non-Barbiturate Hypnotic—Nitrazepam

Published online by Cambridge University Press:  29 January 2018

Ijaz Haider
Ijaz Haider*
Affiliation:
University of Edinburgh Department of Psychiatry, Morningside Park, Edinburgh, 10
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Extract

The need for an acceptable, effective non-barbiturate hypnotic has long been recognized. Nitrazepam (Mogadon), an analogue of chlordiazepoxide with a chemical formula: 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one recently became available for trial. It has been reported to be a safe and effective hypnotic (General Practitioner Research Group, Report No. 79, 1965). Peck and Shervington (1966) found 10 mg. of nitrazepam as effective as 200 mg. of amylobarbitone in general hospital patients. In a previous investigation (Haider, 1967) I reported the efficacy of nitrazepam as an hypnotic agent, in comparison to a placebo, in a group of elderly psychiatric inpatients.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 114 , Issue 508 , March 1968 , pp. 337 - 343
Copyright
Copyright © Royal College of Psychiatrists, 1968 

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