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Double-Blind Comparison of Nortriptyline and Amitriptyline in Depressive Illness

Published online by Cambridge University Press:  29 January 2018

M. R. Leahy  and
Ian C. A. Martin
M. R. Leahy
Affiliation:
St. James's Hospital, Leeds, 9
Ian C. A. Martin
Affiliation:
St. James's Hospital, Leeds, 9
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Extract

Previous assessments of nortriptyline (Bennett, 1962; Rose and Leahy, 1964) have suggested that it has useful anti-depressant properties, and a preliminary trial in which the present authors were involved (Rose et al., 1965) found that it compared sufficiently favourably with amitriptyline to merit further controlled study.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 113 , Issue 505 , December 1967 , pp. 1433 - 1434
Copyright
Copyright © Royal College of Psychiatrists, 1967 

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References

Bennett, I. F. (1962). “The constellation of depression: its treatment with nortriptyline: clinical evaluation of nortriptyline.” J. nerv. ment. Dis., 135, 59.CrossRefGoogle Scholar
Hamilton, M. (1960). “A rating scale for depression.” J. Neurol. Neurosurg. Psychiat., 23, 56–62.Google Scholar
Leahy, M. R., and Rose, J. T. (1964). “A preliminary study of nortriptyline in depression.” Amer. J. Psychiat., 121, 72–73.Google Scholar
Rose, J. T., Leahy, M. R., Martin, I. C. A., and Westhead, J. T. (1965). “A comparison of amitriptyline and nortriptyline in depression.” Brit. J. Psychiat., 111, 1101–1103.Google Scholar
Wilson, I. C., Vernon, J. T., Guin, T., and Sandifer, M. G. (1963). “A controlled study of the treatments of depression.” J. Neuropsychiat., 4, 331–337.Google Scholar
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