Hostname: page-component-cd9895bd7-8ctnn Total loading time: 0 Render date: 2024-12-31T14:56:43.206Z Has data issue: false hasContentIssue false
  • English
  • Français

Cousin Marriages and Schizophrenia in Saudi Arabia

Published online by Cambridge University Press:  02 January 2018

Kutaiba Chaleby  and
T. A. Tuma
Kutaiba Chaleby*
Affiliation:
Department of Medicine, King Faisal Specialist Hospital and Research Centre, PO Box 3354, Riyadh 11211, Saudi Arabia
T. A. Tuma
Affiliation:
Riyadh Psychiatric Hospital, Riyadh 11196, Saudi Arabia
*
∗Correspondece
Get access Rights & Permissions [Opens in a new window]

Abstract

The rate and degree of consanguinity in the parents of 143 schizophrenics who satisfied the DSM-III diagnostic criteria, was compared in the same number of controls matched for age, sex and socioeconomic class. A family history of disorders suggestive of schizophrenia in the offspring of consanguineous parents who were schizophrenic, was compared with the incidence of a similar history in the schizophrenic offspring of non-consanguineous parents. There was no statistically significant difference in the former, but there was in the latter. This finding supports the theory of a familial tendency towards schizophrenia and the possibility of recessive or a multigene pattern of inheritance.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 150 , Issue 4 , April 1987 , pp. 547 - 549
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ahmed, A. H. (1979) Consanguinity and schizophrenia in Sudan. British Journal of Psychiatry, 134, 635–636.Google Scholar
Benjamin, L. S. (1976) A reconstruction of the Kety and associates' study of genetic factors in the transmission of schizophrenia. American Journal of Psychiatry, 133, 1129–1133.Google Scholar
Fischer, M. (1973) Genetic and environmental factors in schizophrenia. Acta Psychiatrica Scandinavica, (suppl.), 238, 9–142.Google Scholar
Gottesman, I. I. & Shields, J. (1966) Schizophrenia in twins: 16 years' consecutive admissions to a psychiatric clinic. British Journal of Psychiatry, 112, 809–814.Google Scholar
Hasanien, M. M. (1984) Beduin Sociology. Riyadh, Kingdom of Saudi Arabia: Okadh Publishing.Google Scholar
Jackson, D. D. (1960) A critique of the literature on the genetics of schizophrenics. In The Etiology of Schizophrenia, (ed. D. D. Jackson). New York: Basic Books.Google Scholar
Kallman, F. J. (1938) The Genetics of Schizophrenia. New York: Augustin.Google Scholar
Kety, S. S., Rosenthal, D., Wender, P. H., Schulsinger, F. & Jacobsen, B. (1975) Mental illness in the biological and adoptive families of adopted individuals who have become schizophrenic: a preliminary report based on psychiatric interviews. In Genetic Research in Psychiatry, (ed. R. R. Fieve, D. Rosenthal & H. Brill). Baltimore: Johns Hopkins University Press.Google Scholar
Kringlen, E. (1967) Heredity and Environment in the Functional Psychoses. London: Heinemann.Google Scholar
Pollin, W., Allen, M. G., Hoffer, A., Stabenau, J. R. & Hrubec, Z. (1969) Psychopathology in 15,909 pairs of veteran twins. American Journal of Psychiatry, 126, 597–602.Google Scholar
Prasad, A. J. (1985) First cousin marriages and psychiatric morbidity. Canadian Journal of Psychiatry, 30, 69–70.Google Scholar
Rudin, E. (1916) Zur Vererbung und Neuentstehung der Dementia Praecox. Berlin: Springer.Google Scholar
Schultz, B. (1932) Zurt Erbpathologie der Schizophrenia. Zeitschrift fuer die Gesamte Neurologic und Psychiatrie, 143, 175–179.Google Scholar
Skoblo, G. V. (1975) Inbreeding and the distribution of schizophrenia in a rural area of Azerbaijan (Russia). Genetika, 11, 149–152.Google Scholar
Slater, E. (1968) A review of earlier evidence on genetic factors in schizophrenia. In The Transmission of Schizophrenia (ed. p. Rosenthal & S. S. Kety). Oxford: Pergamon Press.Google Scholar
Tienari, P. (1963) Psychiatric illnesses in identical twins. Acta Psychiatrica Scandinavicam (Suppl. 171), 1–195.Google Scholar
Zerbin-Rudin, E. (1967) Endogene Psychosen. In Humangenetik, ein kurzes Handbuch, (ed. P. E. Becker). Stuttgart: Thieme.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.