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Concurrent Validity of the Opcrit Diagnostic System

Comparison of OPCRIT Diagnoses with Consensus Best-Estimate Lifetime Diagnoses

Published online by Cambridge University Press:  02 January 2018

Nick Craddock ,
Philip Asherson ,
Michael J. Owen ,
Julie Williams ,
Peter McGuffin  and
Anne E. Farmer
Nick Craddock*
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Philip Asherson
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Michael J. Owen
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Julie Williams
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Peter McGuffin
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Anne E. Farmer
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
*
Dr Nick Craddock, Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN. Fax: 01222 74839. email: [email protected]
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Abstract

Background

OPCRIT (a suite of computer programs that allow data entry and generate diagnoses according to 12 operational diagnostic systems) is used in a wide range of psychiatric research including both European Science Foundation and NIMH research initiatives in the molecular genetics of mental disorders. We examined its concurrent validity in 100 subjects collected for linkage studies of Bipolar Disorder and Schizophrenia.

Method

We compared diagnoses generated by OPCRIT from data rated by two trained clinicians with diagnoses made according to consensus, best-estimate, lifetime procedures by the same two raters according to DSM–III–R and RDC classifications.

Results

Good to excellent agreement was achieved between OPCRIT diagnoses and those made by consensus best-estimate procedures.

Conclusions

OPCRIT provides a convenient, reliable, rapid and valid approach to polydiagnostic assessment that can be used as an adjunct to conventional (but time consuming) best-estimate consensus diagnostic procedures.

Type
Papers
Information
The British Journal of Psychiatry , Volume 169 , Issue 1 , July 1996 , pp. 58 - 63
Copyright
Copyright © 1996 The Royal College of Psychiatrists 

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