Hostname: page-component-78c5997874-4rdpn Total loading time: 0 Render date: 2024-11-06T02:37:40.977Z Has data issue: false hasContentIssue false
  • English
  • Français

Comparison of Electroconvulsive Therapy with Imipramine in Endogenous Depression: A Double Blind Study

Published online by Cambridge University Press:  29 January 2018

B. N. Gangadhar ,
R. L. Kapur  and
S. Kalyanasundaram
B. N. Gangadhar
Affiliation:
Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore 560 029, India
R. L. Kapur*
Affiliation:
Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore 560 029, India
S. Kalyanasundaram
Affiliation:
Department of Psychiatry, National Institute of Mental Health and Neuro Sciences, Bangalore 560 029, India
*
∗ Correspondence and reprints.
Get access Rights & Permissions [Opens in a new window]

Summary

Electroconvulsive therapy was compared with imipramine in the treatment of endogenous depression in a double blind randomized controlled trial. Both treatments produced equally significant improvement which was equally maintained till the end of six months. However ECT produced its effects quicker with lesser subjective side effects to the patient. ECT did not cause any organic brain dysfunction as assessed at the end of three and six months.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 141 , Issue 4 , October 1982 , pp. 367 - 371
Copyright
Copyright © Royal College of Psychiatrists, 1982 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Abrams, R., Taylor, M. A., Mayman, M. & Ramakrishna, N. (1979) Unipolar mania revisited. Journal of Affective Disorders, 1, 59–68.CrossRefGoogle ScholarPubMed
Crome, P. & Newman, B. (1979) The problem of tricyclic poisoning. Post-graduate Medical Journal, 55, 528–32.Google Scholar
Crow, T. J. & Johnstone, E. (1978) ECT—Does it work? Trends in Neurosciences, 1, 51–2.Google Scholar
Feighner, J. P., Robin, E., Guze, S. B., Woodruff, R. A., Winokur, G. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.CrossRefGoogle ScholarPubMed
Freeman, C. P. L., Basson, J. V. & Crighton, A. (1978) Double blind controlled trial of electro convulsive therapy (ECT) and simulated ECT in depressive illness. Lancet, i, 738–40.Google Scholar
Hamilton, M. (1967) Development of a rating scale for primary depressive illness. British Journal of Clinical Psychology, 6, 278–96.Google Scholar
Johnstone, E. J., Deaken, J. F. W., Lawler, P., Frith, C. D., Stevens, M., Metherson, K. & Crow, T. J. (1980) The Northwick Park trial on ECT. Lancet, 2, 1319–20.Google Scholar
Kapur, M. (1978) A short screening battery of tests to detect organic brain dysfunction. Journal of Clinical Psychology, 34, 104–11.Google Scholar
Kapur, R. L., Chandrashekar, C. R., Kapur, M. & Kaliaperumal, V. G. (1981) Social dysfunctioning as a measure of severity of psychiatric illness. Indian Journal of Psychiatry, 23, 27–32.Google Scholar
Kendell, R. E. (1978) Electro convulsive therapy (editorial). Proceedings of Royal College of Medicine, 71, 319–20.Google Scholar
Klicpera, C., Albert, W. & Strain, F. (1979) Effects of somatic treatments on mood in endogenous depression. Acta Psychiatrica Scandinavica, 60, 129–36.CrossRefGoogle ScholarPubMed
Lambourn, J. & Gill, D. A. (1978) Controlled comparison of simulated and real ECT. British Journal of Psychiatry, 133, 514–19.Google Scholar
Pocock, S. J. (1980) The role of statistics in medical research. British Journal of Psychiatry, 137, 188–90.Google Scholar
Proudfoot, A. T. & Park, J. (1978) Changing patterns in drugs used for self poisoning. British Medical Journal, i, 90.CrossRefGoogle Scholar
Robin, A. A. & Harris, J. A. (1962) A controlled comparison of imipramine and electroplexy. Journal of Mental Science, 108, 217–19.Google Scholar
Royal College of Psychiatrists (1977) Memorandum on the use of ECT. British Journal of Psychiatry, 131, 261–72.Google Scholar
Weeks, D., Freeman, C. P. L. & Kendell, R. E. (1980) ECT III: Enduring cognitive deficits? British Journal of Psychiatry, 137, 26–37.Google Scholar
West, E. D. (1980) Electric convulsion therapy in depression: A double-blind controlled trial. British Medical Journal, 282, 355–6.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.