Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-22T16:23:16.513Z Has data issue: false hasContentIssue false
  • English
  • Français

Comparative Effects of Seven Antidepressant Regimes on Appetite, Weight and Carbohydrate Preference

Published online by Cambridge University Press:  29 January 2018

Brian Harris ,
John Young  and
Bill Hughes
Brian Harris*
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine, Cardiff
John Young
Affiliation:
Department of Psychological Medicine, St. Thomas' Hospital, London, SW1
Bill Hughes
Affiliation:
David Rice Hospital, Norwich
*
Correspondence
Get access Rights & Permissions [Opens in a new window]

Abstract

Appetite, weight, and preference for carbohydrate-containing food were followed in patients treated in double-blind trials of seven antidepressant regimes. Trimipramine and isocarboxazid combined had a significant effect in increasing appetite, carbohydrate preference, and weight; in patients who had lost appetite at presentation and were on this treatment, improvement in Hamilton score was linked to increase in weight–a finding not true of the other treatments.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 148 , Issue 5 , May 1986 , pp. 590 - 592
Copyright
Copyright © 1986 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Statistics were carried out by Robert Newcombe, PhD Department of Medical Statistics, University of Wales College of Medicine, Heath Park, Cardiff.

References

Cooper, S. J. & Sanger, D. J. (1984) Endophinergic mechanisms in food, salt, and water intake: an overview. Appetite, 5, 1–6.Google Scholar
Crisp, A. H. & Stonehill, E. (1976) Sleep, Nutrition & Mood. Chichester: John Wiley.Google Scholar
Harris, B., Young, J. & Hughes, B. (1984) Appetite and weight change in patients presenting with depressive illness. Journal of Affective Disorders, 6, 331–339.Google Scholar
Harris, B., Young, J. & Hughes, B. (1984) Changes occurring in appetite and weight during short-term antidepressant treatment. British Journal of Psychiatry. 123, 501–507.Google Scholar
Paykel, E. S., Mueller, P. S. & De la Vergue, P. M. (1973) Amitriptyline, weight gain and carbohydrate craving—a side effect. British Journal of Psychiatry, 123, 501–507.Google Scholar
Young, J. R. P., Hughes, W. C. & Lader, M. H. (1976) A controlled comparison of flupenthixol and amitriptyline in depressed outpatients. British Medical Journal, 1, 1116–1118.Google Scholar
Young, J. R. P., Hughes, W. C. & Lader, M. H. (1979) Controlled trial of trimipramine, mono-amine oxidase inhibitors and combined treatment in depressed outpatients. British Medical Journal, 2, 1315–1117.CrossRefGoogle Scholar
Submit a response

eLetters

No eLetters have been published for this article.