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Clinical use of High-Dose Neuroleptics

Published online by Cambridge University Press:  02 January 2018

Steven R. Hirsch
Affiliation:
Royal College of Psychiatrists
Thomas R. E. Barnes*
Affiliation:
Royal College of Psychiatrists
*
Department of Psychiatry, Charing Cross and Westminster Medical School, London W6 8RP

Abstract

There has been increasing public concern about the risks of high-dose antipsychotic (neuroleptic) treatment, arising in part from an, as yet unproven, association between high-dose treatment and death in a small minority of patients. The clinical issues related to the use of neuroleptics in doses exceeding the maximum recommended in the British National Formulary (BNF) were discussed at the Psychopharmacology Subcommittee. When, if ever, should the recommended doses be exceeded?

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Comment
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Copyright © The Royal College of Psychiatrists 

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Footnotes

1.

The contents of this paper from the Psychopharmacology Subcommittee of the Royal College of Psychiatrists are the responsibility of the authors but are submitted only after being read and approved by the Subcommittee.

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