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Clinical Assessment and Performance Tasks in Depression: a Comparison of Amitriptyline and Trazodone

Published online by Cambridge University Press:  02 January 2018

W. A. Botros ,
S. I. Ankier ,
R. G. Priest ,
I. C. McManus ,
J. Steinert  and
Z. Y. Samir
W. A. Botros
Affiliation:
St Mary's Hospital Medical School
S. I. Ankier
Affiliation:
Roussel Laboratories Ltd, Charterhouse Clinical Research Unit Ltd
R. G. Priest*
Affiliation:
Academic Department of Psychiatry
I. C. McManus
Affiliation:
St Mary's Hospital Medical School
J. Steinert
Affiliation:
Hammersmith Hospital
Z. Y. Samir
Affiliation:
St Mary's Hospital Medical School
*
∗St Mary's Hospital Medical School, Praed Street, London W2 1NY
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Abstract

Depression, anxiety and psychomotor performance were assessed in 20 depressed patients during double-blind treatment with amitriptyline or trazodone. There was no difference in onset of antidepressant or anxiolytic action. No decrement or improvement on computerised tasks was found. Dry mouth was significantly more frequent and severe with amitriptyline.

Type
Papers
Information
The British Journal of Psychiatry , Volume 155 , Issue 4 , October 1989 , pp. 479 - 482
Copyright
Copyright © Royal College of Psychiatrists 1989 

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