Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-19T07:14:06.814Z Has data issue: false hasContentIssue false
  • English
  • Français

Changes occurring in Appetite and Weight during Short-Term Antidepressant Treatment

Published online by Cambridge University Press:  29 January 2018

Brian Harris ,
John Young  and
Bill Hughes
Brian Harris*
Affiliation:
Department of Psychological Medicine, University Hospital of Wales, Heath Park, Cardiff
John Young
Affiliation:
London
Bill Hughes
Affiliation:
David Rice Hospital, Norwich
*
∗Correspondence
Get access Rights & Permissions [Opens in a new window]

Summary

Changes in appetite and weight were recorded in mild to moderately depressed out-patients during the course of clinical trials of various antidepressant drugs. After six weeks, differences due to treatment regimes were minimal. Patients who on becoming depressed experienced severe changes in appetite and weight in either direction, tended to return to normal. The significant associations of appetite and weight change during treatment were with weight, appetite, and carbohydrate preference at presentation, and also with the ‘appetite history’ and ‘weight history’. The associations with the degree of depression were relatively minor.

Type
Research Article
Information
The British Journal of Psychiatry , Volume 145 , Issue 6 , December 1984 , pp. 645 - 648
Copyright
Copyright © 1984 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bruch, H. (1974) Eating Disorders: Obesity, Anorexia and the Person Within. New York: Basic Books.Google Scholar
Crisp, A. H. (1980) Sleep, activity, nutrition and mood. British Journal of Psychiatry, 137, 1–7.Google Scholar
Feighner, J. P., Robins, E., Guze, S. B., Woodruff, R. A., Winokur, G. & Munoz, R. (1972) Diagnostic criteria for use in psychiatric research. Archives of General Psychiatry, 26, 57–63.Google Scholar
Gottfries, C. G. (1981) Influence of depression and anti-depressants on weight. Acta Psychiatrica Scandinavica Supplementia, 290, vol. 63, 353.CrossRefGoogle Scholar
Harris, B., Young, J. & Hughes, B. (1984) Appetite and weight change in patients presenting with depressive illness. Journal of Affective Disorders, 6, 331–339.Google Scholar
Meyer, J. E. & Pudel, V. E. (1977). Experimental feeding in man: A behavioural approach to obesity. Psychosomatic Medicine, 39, 3, 153–157.CrossRefGoogle Scholar
Paykel, E. S., Mueller, P. S. & de la Vergue, P. M. (1973) Amitriptyline, weight gain and carbohydrate craving: A side effect. British Journal of Psychiatry, 123, 501–507.Google Scholar
Polivy, J. & Herman, C. P. (1976) Clinical depression and weight change: A complex relation. Journal of Abnormal Psychology, 85, 3, 338–340.Google Scholar
Rodin, J. (1978) Has the distinction between internal versus external control of feeding outlived its usefulness? Recent Advances in Obesity Research, 2, 75–85.Google Scholar
Young, J. P. R., Hughes, W. C. & Lader, M. H. (1976). A controlled comparison of flupenthixol and amitriptyline in depressed outpatients. British Medical Journal, 1, 1116–1118.Google Scholar
Young, J. P. R., Lader, M. H. & Hughes, W. C. (1979). Controlled trial of trimipramine, mono-oxidase inhibitors, and combined treatment in depressed outpatients. British Medical Journal, 2, 1315–1317.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.